Evidence map›Paper›PMID 21939377›Full record

ReviewAnnual review of microbiology2011

Motility and chemotaxis in Campylobacter and Helicobacter .

Paphavee Lertsethtakarn, Karen M Ottemann, David R Hendrixson

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 319 citations in OpenAlex.

  1. Trial
  2. Characterization ofJournal of bacteriology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The ancient E-ring in bacterial flagellar motors.FEMS microbiology reviews · 2026
    Review
  8. Measurement of the Cell-Body Rotation of Leptospira.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. Diversity of Bacteria.Progress in molecular and subcellular biology · 2026
    Review
  10. Cas9 modulatesMicrobiology (Reading, England) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Improvement and tolerance mechanisms ofFrontiers in microbiology · 2025
    Article
  15. Frontiers in microbiology · 2025
    Article
  16. Article
  17. Pathogens (Basel, Switzerland) · 2024
    Review
  18. Increased Motility inInternational journal of molecular sciences · 2024
    Article
  19. Article
  20. Article

124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Paphavee LertsethtakarnDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California 95064, USA.
Karen M Ottemann
David R Hendrixson
University of California, Santa Cruz · USThe University of Texas Southwestern Medical Center · US

Funding

Flagellar Motor Biogenesis in Polarly-Flagellated Bacterial PathogensR01AI065539 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI DAVID R HENDRIXSON · 2006 to 2026
$9.2M
Roles for Motility in Helicobactor pylori pathogenesisR01AI050000 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI OTTEMANN, KAREN M · 2002 to 2011
$3.6M
NIAID NIH HHS AI050000NIAID NIH HHS R01 AI050000NIAID NIH HHS R01 AI065539
6 · The paper itself

Abstract

Flagellar motility of Campylobacter jejuni and Helicobacter pylori influences host colonization by promoting migration through viscous milieus such as gastrointestinal mucus. This review explores mechanisms C. jejuni and H. pylori employ to control flagellar biosynthesis and chemotactic responses. These microbes tightly control the activities of σ(54) and σ(28) to mediate ordered flagellar gene expression. In addition to phase-variable and posttranslational mechanisms, flagellar biosynthesis is regulated spatially and numerically so that only a certain number of organelles are placed at polar sites. To mediate chemotaxis, C. jejuni and H. pylori combine basic chemotaxis signal transduction components with several accessory proteins. H. pylori is unusual in that it lacks a methylation-based adaptation system and produces multiple CheV coupling proteins. Chemoreceptors in these bacteria contain nonconserved ligand binding domains, with several chemoreceptors matched to environmental signals. Together, these mechanisms allow for swimming motility that is essential for colonization.

Indexed as

ChemotaxisBacterial ProteinsCampylobacter jejuniFlagellaGene Expression Regulation, BacterialHelicobacter pyloriBacterial Proteins

Identifiers

PMID21939377
PMCPMC6238628
OpenAlexW2012750529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.