Evidence map›Paper›PMID 21938058›Full record

ArticleNature2011

Ageing: longevity hits a roadblock.

David B Lombard, Scott D Pletcher, Carles Cantó, Johan Auwerx

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Balancing NADCellular and molecular life sciences : CMLS · 2022
    Review
  3. Article
  4. Review
  5. Review
  6. Biochemical Genetic Pathways that Modulate Aging in Multiple Species.Cold Spring Harbor perspectives in medicine · 2015
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Ribosomal RNA gene repeats, their stability and cellular senescence.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2014
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David B LombardDepartment of Pathology and Institute of Gerontology, University of Michigan, Ann Arbor, Michigan 48109, USA. davidlom@umich.edu
Scott D Pletcher
Carles Cantó
Johan Auwerx

Funding

Regulation of one carbon metabolism and epigenetics by SIRT5R01GM101171 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOMBARD, DAVID BENNER · 2012 to 2021
$2.6M
NIGMS NIH HHS R01 GM101171
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDrosophila melanogasterDrosophila ProteinsFemaleHistone DeacetylasesLongevityMaleSirtuinsCaenorhabditis elegans ProteinsDrosophila ProteinsHistone DeacetylasesSIR-2.1 protein, C elegansSirt2 protein, DrosophilaSirtuins

Identifiers

PMID21938058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.