ArticleNature2011
Molecular organization of vomeronasal chemoreception.
Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
173 citing papers in PubMed, 334 citations in OpenAlex.
- Male and female mice scent mark during social communication regardless of sexual motivation or partner identity.Cell reports · 2026Article
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- Bile acid chemosensation in mammals supports species and gut microbiome evaluation.bioRxiv : the preprint server for biology · 2026Article
- Synaptic Inhibition in the Accessory Olfactory Bulb Regulates Pheromone Location Learning and Memory.FASEB bioAdvances · 2026Article
- Perception and neural representation of intermittent odor stimuli in mice.Nature communications · 2026Article
- Cnpy1 is a candidate endoplasmic reticulum chaperone of vomeronasal type 2 GPCRs.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Kirrel3 homophilic adhesion function is required for male-directed aggression and vomeronasal acuity to urine chemosignals.Frontiers in cellular neuroscience · 2026Article
- Histochemical Properties of the Vomeronasal System in Hokkaido Sika Deer (Animals : an open access journal from MDPI · 2025Article
- Combinatorial responsiveness of chemosensory neurons in mouse explants revealed by DynamicNeuroTracker.Cell reports methods · 2025Article
- Convergent reduction of olfactory genes and olfactory bulb size in mammalian species at altitude.Current biology : CB · 2025Article
- Amplification of Olfactory Transduction Currents Implements Sparse Stimulus Encoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The neurobiology of parenting and infant-evoked aggression.Physiological reviews · 2025Review
- Article
- Development of an rpS6-Based Ex Vivo Assay for the Analysis of Neuronal Activity in Mouse and Human Olfactory Systems.International journal of molecular sciences · 2024Article
- Article
- Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice.eLife · 2024Article
- Amplification of olfactory transduction currents implements sparse stimulus encoding.bioRxiv : the preprint server for biology · 2024Article
- Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal organ at Single Cell Resolution.bioRxiv : the preprint server for biology · 2024Article
- The vomeronasal system of the wolf (Canis lupus signatus): The singularities of a wild canid.Journal of anatomy · 2024Article
- Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The vomeronasal organ (VNO) has a key role in mediating the social and defensive responses of many terrestrial vertebrates to species- and sex-specific chemosignals. More than 250 putative pheromone receptors have been identified in the mouse VNO, but the nature of the signals detected by individual VNO receptors has not yet been elucidated. To gain insight into the molecular logic of VNO detection leading to mating, aggression or defensive responses, we sought to uncover the response profiles of individual vomeronasal receptors to a wide range of animal cues. Here we describe the repertoire of behaviourally and physiologically relevant stimuli detected by a large number of individual vomeronasal receptors in mice, and define a global map of vomeronasal signal detection. We demonstrate that the two classes (V1R and V2R) of vomeronasal receptors use fundamentally different strategies to encode chemosensory information, and that distinct receptor subfamilies have evolved towards the specific recognition of certain animal groups or chemical structures. The association of large subsets of vomeronasal receptors with cognate, ethologically and physiologically relevant stimuli establishes the molecular foundation of vomeronasal information coding, and opens new avenues for further investigating the neural mechanisms underlying behaviour specificity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.