Evidence map›Paper›PMID 21936953›Full record

ArticleParasites & vectors2011

Identification of mosquito repellent odours from Ocimum forskolei.

Teun Dekker, Rickard Ignell, Maedot Ghebru, Robert Glinwood, Richard Hopkins

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 74 citations in OpenAlex.

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  8. Structure modelling of odorant receptor fromComputational and structural biotechnology journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Teun DekkerDivision of Chemical Ecology, Department of Crop Science, Swedish University of Agricultural Sciences PO 44, Alnarp, SE-23053, Sweden. teun.dekker@slu.se
Rickard Ignell
Maedot Ghebru
Robert Glinwood
Richard Hopkins
Swedish University of Agricultural Sciences · SEUniversity of Asmara · ER

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNative mosquito repellent plants have a good potential for integrated mosquito control in local settings. Ocimum forskolei, Lamiaceae, is used in Eritrea as a spatial mosquito repellent inside houses, either through crushing fresh plants or burning dry plants. We verified whether active repellent compounds could be identified using gas-chromatography coupled electroantennogram recordings (GC-EAD) with headspace extracts of crushed plants.

resultsEAD active compounds included (R)-(-)-linalool, (S)-(+)-1-octen-3-ol, trans-caryophyllene, naphthalene, methyl salicylate, (R)-(-)-α-copaene, methyl cinnamate and (E)-ocimene. Of these compounds (R)-(-)-linalool, methyl cinnamate and methyl salicylate reduced landing of female Aedes aegypti on human skin-odor baited tubes. The latter two are novel mosquito repellent compounds.

conclusionsThe identification of mosquito repellent compounds contributes to deciphering the mechanisms underlying repulsion, supporting the rational design of novel repellents. The three mosquito repellent compounds identified in this study are structurally dissimilar, which may indicate involvement of different sensory neurons in repulsion. Repulsion may well be enhanced through combining different repellent plants (or their synthetic mimics), and can be a locally sustainable part in mosquito control efforts.

Indexed as

AedesAnimalsFemaleGas Chromatography-Mass SpectrometryInsect RepellentsMaleMosquito ControlOcimumOdorantsPlant ExtractsVolatile Organic CompoundsInsect RepellentsPlant ExtractsVolatile Organic Compounds

Identifiers

PMID21936953
PMCPMC3189156
OpenAlexW2128240453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.