ArticleBMC genomics2011
Spatial analysis of biomineralization associated gene expression from the mantle organ of the pearl oyster Pinctada maxima.
Article in BMC genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 84 citations in OpenAlex.
- The chromosome-level genome assembly and annotation of the silver-lipped pearl oyster, Pinctada maxima.Scientific data · 2025Article
- Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes.Biology open · 2025Article
- Proteomic and Transcriptomic Responses Enable Clams to Correct the pH of Calcifying Fluids and Sustain Biomineralization in Acidified Environments.International journal of molecular sciences · 2022Article
- Evolution of Epidermal Growth Factor (EGF)-like and Zona Pellucida Domains Containing Shell Matrix Proteins in Mollusks.Molecular biology and evolution · 2022Article
- Transcriptome analysis of the bivalve Placuna placenta mantle reveals potential biomineralization-related genes.Scientific reports · 2022Article
- Identification of a coproporphyrinogen-III oxidase gene and its correlation with nacre color in Hyriopsis cumingii.PloS one · 2022Article
- Characterization of Thrombospondin Type 1 Repeat in Haliotis diversicolor and Its Possible Role in Osteoinduction.Marine biotechnology (New York, N.Y.) · 2021Article
- Dilution of Seawater Affects the CaFrontiers in physiology · 2020Article
- Evolution and diversity of alpha-carbonic anhydrases in the mantle of the Mediterranean mussel (Mytilus galloprovincialis).Scientific reports · 2019Article
- Expressions of Shell Matrix Protein Genes in the Pearl Sac and Its Correlation with Pearl Weight in the First 6 Months of Pearl Formation in Hyriopsis cumingii.Marine biotechnology (New York, N.Y.) · 2019Article
- Cultured Pearl Surface Quality Profiling by the Shell Matrix Protein Gene Expression in the Biomineralised Pearl Sac Tissue of Pinctada margaritifera.Marine biotechnology (New York, N.Y.) · 2018Article
- Identifying genes and regulatory pathways associated with the scleractinian coral calcification process.PeerJ · 2017Article
- Identification and Characterization of the Lysine-Rich Matrix Protein Family in Pinctada fucata: Indicative of Roles in Shell Formation.Marine biotechnology (New York, N.Y.) · 2016Article
- Aragonite-Associated Mollusk Shell Protein Aggregates To Form Mesoscale "Smart" Hydrogels.ACS omega · 2016Article
- An Antarctic molluscan biomineralisation tool-kit.Scientific reports · 2016Article
- Synergistic Biomineralization Phenomena Created by a Combinatorial Nacre Protein Model System.Biochemistry · 2016Article
- Transcriptome and biomineralization responses of the pearl oyster Pinctada fucata to elevated CO2 and temperature.Scientific reports · 2016Article
- Sea shell diversity and rapidly evolving secretomes: insights into the evolution of biomineralization.Frontiers in zoology · 2016Review
- Differentially-Expressed Genes Associated with Faster Growth of the Pacific Abalone, Haliotis discus hannai.International journal of molecular sciences · 2015Article
- Identification of genes associated with shell color in the black-lipped pearl oyster, Pinctada margaritifera.BMC genomics · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiomineralization is a process encompassing all mineral containing tissues produced within an organism. One of the most dynamic examples of this process is the formation of the mollusk shell, comprising a variety of crystal phases and microstructures. The organic component incorporated within the shell is said to dictate this architecture. However general understanding of how this process is achieved remains ambiguous. The mantle is a conserved organ involved in shell formation throughout molluscs. Specifically the mantle is thought to be responsible for secreting the protein component of the shell. This study employs molecular approaches to determine the spatial expression of genes within the mantle tissue to further the elucidation of the shell biomineralization.
resultsA microarray platform was custom generated (PmaxArray 1.0) from the pearl oyster Pinctada maxima. PmaxArray 1.0 consists of 4992 expressed sequence tags (ESTs) originating from mantle tissue. This microarray was used to analyze the spatial expression of ESTs throughout the mantle organ. The mantle was dissected into five discrete regions and analyzed for differential gene expression with PmaxArray 1.0. Over 2000 ESTs were determined to be differentially expressed among the tissue sections, identifying five major expression regions. In situ hybridization validated and further localized the expression for a subset of these ESTs. Comparative sequence similarity analysis of these ESTs revealed a number of the transcripts were novel while others showed significant sequence similarities to previously characterized shell related genes.
conclusionsThis investigation has mapped the spatial distribution for over 2000 ESTs present on PmaxArray 1.0 with reference to specific locations of the mantle. Expression profile clusters have indicated at least five unique functioning zones in the mantle. Three of these zones are likely involved in shell related activities including formation of nacre, periostracum and calcitic prismatic microstructure. A number of novel and known transcripts have been identified from these clusters. The development of PmaxArray 1.0, and the spatial map of its ESTs expression in the mantle has begun characterizing the molecular mechanisms linking the organics and inorganics of the molluscan shell.
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