Evidence map›Paper›PMID 21935438›Full record

Trial reportPloS one2011

Short and intense tailor-made notched music training against tinnitus: the tinnitus frequency matters.

Henning Teismann, Hidehiko Okamoto, Christo Pantev

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Pooled it
  3. Guideline
  4. Trial
  5. A Randomized, Controlled Trial of Notched Music Therapy for Tinnitus Patients.The journal of international advanced otology · 2021
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  11. Music Therapy and Tinnitus Treatment: Systematic Review and Meta-Analysis.International archives of otorhinolaryngology · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. The Current State of Tinnitus Diagnosis and Treatment: a Multidisciplinary Expert Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  16. Review
  17. Review
  18. Tinnitus Guidelines and Their Evidence Base.Journal of clinical medicine · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Henning TeismannInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Muenster, Germany. h.teismann@uni-muenster.de
Hidehiko Okamoto
Christo Pantev

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinnitus is one of the most common diseases in industrialized countries. Here, we developed and evaluated a short-term (5 subsequent days) and intensive (6 hours/day) tailor-made notched music training (TMNMT) for patients suffering from chronic, tonal tinnitus. We evaluated (i) the TMNMT efficacy in terms of behavioral and magnetoencephalographic outcome measures for two matched patient groups with either low (≤8 kHz, N = 10) or high (>8 kHz, N = 10) tinnitus frequencies, and the (ii) persistency of the TMNMT effects over the course of a four weeks post-training phase. The results indicated that the short-term intensive TMNMT took effect in patients with tinnitus frequencies ≤8 kHz: subjective tinnitus loudness, tinnitus-related distress, and tinnitus-related auditory cortex evoked activity were significantly reduced after TMNMT completion. However, in the patients with tinnitus frequencies >8 kHz, significant changes were not observed. Interpreted in their entirety, the results also indicated that the induced changes in auditory cortex evoked neuronal activity and tinnitus loudness were not persistent, encouraging the application of the TMNMT as a longer-term training. The findings are essential in guiding the intended transfer of this neuro-scientific treatment approach into routine clinical practice.

Indexed as

AdultFemaleHumansMaleMusic TherapyTinnitusTreatment OutcomeYoung Adult

Identifiers

PMID21935438
PMCPMC3174191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.