ArticleJournal of Korean medical science2011
Korean type 2 diabetes patients have multiple adenomatous polyps compared to non-diabetic controls.
Article in Journal of Korean medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04477694 (The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Modifiable lifestyle and metabolic risk factors for colorectal polyps: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Type 2 diabetes mellitus and risk of colorectal adenoma: a meta-analysis of observational studies.BMC cancer · 2016Pooled it
- Type 2 Diabetes and Gastrointestinal Cancers: Risk Associations and Awareness of Screening Challenges.Cancers · 2025Review
- Overweight and obesity are associated with colorectal neoplasia in an Australian outpatient population.Scientific reports · 2024Observational
- Metformin administration in prevention of colorectal polyps in type 2 diabetes mellitus patients.World journal of clinical cases · 2024Article
- Age-Specific Differences in the Risk of Colorectal Precursor Lesions Among Patients with Type 2 Diabetes Undergoing Surveillance Colonoscopy.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps.Cancer prevention research (Philadelphia, Pa.) · 2021Observational
- Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment.Diabetes & metabolism journal · 2019Review
- Diabetes mellitus and hyperglycemia control on the risk of colorectal adenomatous polyps: a retrospective cohort study.BMC family practice · 2018Article
- Significantly higher rates of multiple and proximally located adenomas among patients with diabetes mellitus: A cross-sectional population-based study.United European gastroenterology journal · 2017Article
- Diabetes Mellitus and Site-specific Colorectal Cancer Risk in Korea: A Case-control Study.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2016Article
- Metformin and breast and gynecological cancer risk among women with diabetes.BMJ open diabetes research & care · 2015Article
- The relationship between different glycemic statuses and colon polyps in a Taiwanese population.Journal of gastroenterology · 2014Article
- Type 2 diabetes and the risk of colorectal adenomas: Black Women's Health Study.American journal of epidemiology · 2014Article
- Risk of colonic cancer is not higher in the obese Lep(ob) mouse model compared to lean littermates.Pathology oncology research : POR · 2013Article
- Metformin and the risk of cancer: time-related biases in observational studies.Diabetes care · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We tested the correlation between diabetes and aggressiveness of colorectal polyps in diabetic patients and matched non-diabetic controls. We retrospectively studied 3,505 type 2 diabetes (T2DM) patients without gastrointestinal symptoms who underwent colonoscopy for colorectal cancer at Samsung Medical Center, Seoul, Korea from August 1995 to August 2009. We matched 495 non-diabetic subjects with colon polyps to the diabetic patients in whom polyps were detected by year of colonoscopy, age, sex and body mass index (BMI). Among the 3,505 T2DM patients screened, 509 were found to have 1,136 colon polyps. Those with diabetes had a greater proportion of adenomatous polyps (62.8% vs 53.6%) compared to the control. Multivariate logistic regression analysis identified DM, male gender, age and BMI as independent risk factors for multiple polyps (more than three polyps). Polyp multiplicity in diabetic patients was significantly associated with male gender (OR 2.360, P = 0.005), age (OR 1.033, P = 0.005) and BMI (OR 1.077, P = 0.028). Neither aspirin nor metformin use affected either size or number of polyps in diabetic patients. Male patients older than 65 yr with T2DM and BMI greater than 25 have increased risk for multiple adenomatous polyps and should be screened with colonoscopy to prevent colorectal cancer.
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