Evidence map›Paper›PMID 21935110›Full record

ArticleOptics express2011

Depth-resolved image mapping spectrometer (IMS) with structured illumination.

Liang Gao, Noah Bedard, Nathan Hagen, Robert T Kester, Tomasz S Tkaczyk

Open access · goldAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Optics express, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 43 citations in OpenAlex.

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  13. Image mapping spectrometry: calibration and characterization.Optical engineering (Redondo Beach, Calif.) · 2012
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liang GaoDepartment of Bioengineering, Rice University, Houston, Texas 77005, USA.
Noah Bedard
Nathan Hagen
Robert T Kester
Tomasz S Tkaczyk
Rice University · US

Funding

Image mapped spectroscopy for snapshot 3-D biomedical imagingR21EB011598 · NIBIB · RICE UNIVERSITY · PI PIERCE, MARK, TKACZYK, TOMASZ S · 2011 to 2012
$394k
Image Slicing Spectrometer (ISS) for high resolution sub-cellular microscopyR21EB009186 · NIBIB · RICE UNIVERSITY · PI TKACZYK, TOMASZ S · 2008 to 2009
$383k
NIBIB NIH HHS R21 EB009186NIBIB NIH HHS R21EB009186NIBIB NIH HHS R21 EB011598NIBIB NIH HHS R21EB011598
6 · The paper itself

Abstract

We present a depth-resolved Image Mapping Spectrometer (IMS) which is capable of acquiring 4D (x, y, z, λ) datacubes. Optical sectioning is implemented by structured illumination. The device's spectral imaging performance is demonstrated in a multispectral microsphere and mouse kidney tissue fluorescence imaging experiment. We also compare quantitatively the depth-resolved IMS with a hyperspectral confocal microscope (HCM) in a standard fluorescent bead imaging experiment. The comparison results show that despite the use of a light source with four orders of magnitude lower intensity in the IMS than that in the HCM, the image signal-to-noise ratio acquired by the IMS is 2.6 times higher than that achieved by the equivalent confocal approach.

Indexed as

AnimalsFluorescent DyesImaging, Three-DimensionalKidneyMiceMicroscopy, ConfocalMicroscopy, FluorescenceMicrospheresOptical PhenomenaSignal Processing, Computer-AssistedSignal-To-Noise RatioFluorescent Dyes

Identifiers

PMID21935110
PMCPMC3190403
OpenAlexW2064708311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.