ArticleBritish journal of cancer2011
Survival from childhood cancer in northern England, 1968-2005.
Article in British journal of cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Worldwide Trends in Survival From Common Childhood Brain Tumors: A Systematic Review.Journal of global oncology · 2019Pooled it
- Article
- Long-term unmet supportive care needs of teenage and young adult (TYA) childhood brain tumour survivors and their caregivers: a cross-sectional survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Childhood cancer incidence and survival trends in Estonia (1970-2016): a nationwide population-based study.BMC cancer · 2020Article
- Social Inequalities Along the Childhood Cancer Continuum: An Overview of Evidence and a Conceptual Framework to Identify Underlying Mechanisms and Pathways.Frontiers in public health · 2019Review
- Incidence and Survival of Childhood Cancer in Korea.Cancer research and treatment · 2016Article
- Emotional/Behavioral problems in children with acute lymphoblastic leukemia: a case-control study.International journal of hematology-oncology and stem cell research · 2014Article
- Socioeconomic variation in survival from childhood leukaemia in northern England, 1968-2010.British journal of cancer · 2013Article
- Does referral to specialist paediatric palliative care services reduce hospital admissions in oncology patients at the end of life?British journal of cancer · 2013Article
- Empiric antibiotic therapy in a child with cancer and suspected septicemia.Pediatric reports · 2012Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer is the second most common cause of death in children in the developed world. The study investigated patterns and trends in survival from childhood cancer in patients from northern England diagnosed 1968-2005.
methodsFive-year survival was analysed using Kaplan-Meier estimation for four successive time periods. Cox regression analysis was used to explore associations with age and demographic factors.
resultsThe study included 2958 cases (1659 males and 1299 females). Five-year survival for all cancers improved significantly from 39% in 1968-1977 to 79% in 1998-2005 (P<0.001). Five-year survival for leukaemia increased from 24% to 81% (P<0.001), lymphoma from 46% to 87% (P<0.001), central nervous system tumours from 43% to 73% (P<0.001), bone tumours from 21% to 75% (P<0.001), soft tissue sarcoma from 30% to 58% (P<0.001) and germ cell tumours from 59% to 97% (P<0.001). Survival was worse for cases of acute lymphoblastic leukaemia (P<0.001) and astrocytoma (P<0.001) aged 10-14 years compared with 0-4-year olds.
conclusionThere were marked improvements in survival over a 38-year time span. Future work should examine factors that could influence further improvement in survival such as diagnosis delays.
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