Evidence map›Paper›PMID 21933376›Full record

Trial reportMalaria journal2011

Cost analysis of school-based intermittent screening and treatment of malaria in Kenya.

Thomas L Drake, George Okello, Kiambo Njagi, Katherine E Halliday, Matthew Ch Jukes, Lindsay Mangham, Simon Brooker

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00878007 (Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00878007 nacompletednot on this map

Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren

TypeinterventionalSponsorLondon School of Hygiene and Tropical MedicineRan2010 to 2012Enrolled5,177ConditionsAnaemia, MalariaArmsIntermittent screening and treatment for malaria, Teacher training on literacy instruction, IST plus literacy instruction programme
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Costs and Cost-Effectiveness of Malaria Control Interventions: A Systematic Literature Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2021
    Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Malaria in school-age children in Africa: an increasingly important challenge.Tropical medicine & international health : TM & IH · 2014
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas L DrakeFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. thomas.drake@lshtm.ac.uk
George Okello
Kiambo Njagi
Katherine E Halliday
Matthew Ch Jukes
Lindsay Mangham
Simon Brooker

Funding

Wellcome Trust 092765
6 · The paper itself

Abstract

backgroundThe control of malaria in schools is receiving increasing attention, but there remains currently no consensus as to the optimal intervention strategy. This paper analyses the costs of intermittent screening and treatment (IST) of malaria in schools, implemented as part of a cluster-randomized controlled trial on the Kenyan coast.

methodsFinancial and economic costs were estimated using an ingredients approach whereby all resources required in the delivery of IST are quantified and valued. Sensitivity analysis was conducted to investigate how programme variation affects costs and to identify potential cost savings in the future implementation of IST.

resultsThe estimated financial cost of IST per child screened is US$ 6.61 (economic cost US$ 6.24). Key contributors to cost were salary costs (36%) and malaria rapid diagnostic tests (RDT) (22%). Almost half (47%) of the intervention cost comprises redeployment of existing resources including health worker time and use of hospital vehicles. Sensitivity analysis identified changes to intervention delivery that can reduce programme costs by 40%, including use of alternative RDTs and removal of supervised treatment. Cost-effectiveness is also likely to be highly sensitive to the proportion of children found to be RDT-positive.

conclusionIn the current context, school-based IST is a relatively expensive malaria intervention, but reducing the complexity of delivery can result in considerable savings in the cost of intervention. (Costs are reported in US$ 2010).

Indexed as

SchoolsAdolescentAntimalarialsChildCosts and Cost AnalysisHumansKenyaMalariaMass ScreeningAntimalarials

Identifiers

PMID21933376
PMCPMC3187739

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.