Evidence map›Paper›PMID 21932156›Full record

SynthesisJournal of autism and developmental disorders2012

Autism spectrum disorder: does neuroimaging support the DSM-5 proposal for a symptom dyad? A systematic review of functional magnetic resonance imaging and diffusion tensor imaging studies.

Laura Pina-Camacho, Sonia Villero, David Fraguas, Leticia Boada, Joost Janssen, Francisco J Navas-Sánchez, Maria Mayoral, Cloe Llorente, Celso Arango, Mara Parellada

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of autism and developmental disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. An Umbrella Review of the Fusion of fMRI and AI in Autism.Diagnostics (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Epilepsy and Autism.Cold Spring Harbor perspectives in medicine · 2016
    Review
  9. Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Why autism must be taken apart.Journal of autism and developmental disorders · 2014
    Article
  17. Article
  18. PET and MR imaging: the odd couple or a match made in heaven?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2013
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Laura Pina-CamachoChild and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, C/Ibiza 43, Madrid 28009, Spain. lpina@iisgm.com
Sonia Villero
David Fraguas
Leticia Boada
Joost Janssen
Francisco J Navas-Sánchez
Maria Mayoral
Cloe Llorente
Celso Arango
Mara Parellada
Hospital General Universitario Gregorio Marañón · ESCentro de Investigación Biomédica en Red de Salud Mental · ESCentro de Investigación Biomédica en Red · ESComplejo Hospitalario de Navarra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systematic review of 208 studies comprising functional magnetic resonance imaging and diffusion tensor imaging data in patients with 'autism spectrum disorder' (ASD) was conducted, in order to determine whether these data support the forthcoming DSM-5 proposal of a social communication and behavioral symptom dyad. Studies consistently reported abnormal function and structure of fronto-temporal and limbic networks with social and pragmatic language deficits, of temporo-parieto-occipital networks with syntactic-semantic language deficits, and of fronto-striato-cerebellar networks with repetitive behaviors and restricted interests in ASD patients. Therefore, this review partially supports the DSM-5 proposal for the ASD dyad.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersDiffusion Magnetic Resonance ImagingImage Interpretation, Computer-AssistedMagnetic Resonance ImagingAsperger SyndromeAutistic DisorderBrainBrain MappingChildChild Behavior DisordersChild Development Disorders, PervasiveHumansLanguage Development DisordersNerve NetOxygenRegional Blood FlowOxygen

Identifiers

PMID21932156
OpenAlexW2137853877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.