Evidence map›Paper›PMID 21931994›Full record

ArticleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2012

HPV typing and its relation with apoptosis in cervical carcinoma from Indian population.

M Shabbir Alam, Asgar Ali, Syed Jafar Mehdi, Nisreen Sherif Alyasiri, Zakia Kazim, Swaraj Batra, A K Mandal, M Moshahid Alam Rizvi

Abstract read
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In one paragraph

Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Mutation analysis of EGFR and its correlation with the HPV in Indian cervical cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  4. The prognosis significance of TGF-β1 and ER protein in cervical adenocarcinoma patients with stage Ib~IIa.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  5. Review
  6. Human papillomavirus oncoproteins and apoptosis (Review).Experimental and therapeutic medicine · 2014
    Article
  7. Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-κB pathway.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013
    Article
  8. Implication of androgen receptor in urinary bladder cancer: a critical mini review.International journal of molecular epidemiology and genetics · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

M Shabbir AlamGenome Biology Lab, Department of Biosciences, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi 110025, India.
Asgar Ali
Syed Jafar Mehdi
Nisreen Sherif Alyasiri
Zakia Kazim
Swaraj Batra
A K Mandal
M Moshahid Alam Rizvi
Jamia Millia Islamia · INMadigan Army Medical Center · USJazan University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Definite progress in understanding the etiology of cervical cancer has been achieved, and some types of human papillomavirus have been established as the central cause of cervical cancer worldwide. This study investigates the human papillomavirus infection and its correlation with apoptosis and clinicopathologic characteristics in squamous cell carcinoma of uterine cervix. Human papillomavirus typing was done by type-specific primers for high-risk human papillomavirus using standard polymerase chain reaction method. Programmed cell death (apoptosis) was determined by terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling assay. Human papillomavirus infection in tissue biopsy of cervical carcinoma was detected in 131 of 135 (97%) cases. Among the positive cases of human papillomavirus, 123 (94%) cases were human papillomavirus type 16, and five (4%) cases were human papillomavirus type 18. Out of 135 cervical carcinoma cases, 81 (60%) cases showed presence of apoptosis. The phenomenon of apoptosis was seen slightly higher in squamous cell carcinoma than in adenocarcinoma (40% in squamous cell carcinoma and 33% in adenocarcinoma). The human papillomavirus infection in cervical cancer might not play any role in the occurrence of apoptosis.

Indexed as

AdultAgedAged, 80 and overApoptosisCarcinomaFemaleHuman papillomavirus 16Human papillomavirus 18HumansIndiaMiddle AgedPapillomavirus InfectionsUterine Cervical NeoplasmsVirology

Identifiers

PMID21931994
OpenAlexW2069969799

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.