ArticlePloS one2011
Metagenome plasticity of the bovine abomasal microbiota in immune animals in response to Ostertagia ostertagi infection.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 76 citations in OpenAlex.
- Escherichia coli is implicated in the development and manifestation of host susceptibility to the roundworm Trichostrongylus colubriformis infections in sheep.Veterinary research · 2025Article
- Interaction between methanotrophy and gastrointestinal nematodes infection on the rumen microbiome of lambs.FEMS microbiology ecology · 2024Article
- Red Cabbage Modulates Composition and Co-Occurrence Networks of Gut Microbiota in a Rodent Diet-Induced Obesity Model.Foods (Basel, Switzerland) · 2023Article
- Differences in Faecal Microbiome Taxonomy, Diversity and Functional Potential in a Bovine Cohort Experimentally Challenged withAnimals : an open access journal from MDPI · 2023Article
- Species interactions, stability, and resilience of the gut microbiota - Helminth assemblage in horses.iScience · 2023Article
- Metagenome reveals caprine abomasal microbiota diversity at early and late stages of Haemonchus contortus infection.Scientific reports · 2023Article
- Microbial community in resistant and susceptible Churra sheep infected by Teladorsagia circumcincta.Scientific reports · 2022Article
- Worms and bugs of the gut: the search for diagnostic signatures using barcoding, and metagenomics-metabolomics.Parasites & vectors · 2022Review
- Article
- Describing the intestinal microbiota of Holstein Fasciola-positive and -negative cattle from a hyperendemic area of fascioliasis in central Colombia.PLoS neglected tropical diseases · 2021Article
- Vaccination against the brown stomach worm, Teladorsagia circumcincta, followed by parasite challenge, induces inconsistent modifications in gut microbiota composition of lambs.Parasites & vectors · 2021Article
- A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome ofAnimals : an open access journal from MDPI · 2021Article
- Emerging interactions between diet, gastrointestinal helminth infection, and the gut microbiota in livestock.BMC veterinary research · 2021Review
- Modulation of Rumen Microbes Through Extracellular Vesicle Released by the Rumen FlukeFrontiers in cellular and infection microbiology · 2021Article
- Infection with the sheep gastrointestinal nematode Teladorsagia circumcincta increases luminal pathobionts.Microbiome · 2020Article
- Variation in gut bacterial composition is associated with Haemonchus contortus parasite infection of sheep.Animal microbiome · 2020Article
- Harnessing the gut microbiome in the fight against anthelminthic drug resistance.Current opinion in microbiology · 2020Review
- Article
- Dysbiosis associated with acute helminth infections in herbivorous youngstock - observations and implications.Scientific reports · 2019Article
- Effect of intestinal tapeworms on the gut microbiota of the common carp, Cyprinus carpio.Parasites & vectors · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Infections in cattle by the abomasal nematode Ostertagia ostertagi result in impaired gastrointestinal function. Six partially immune animals were developed using multiple drug-attenuated infections, and these animals displayed reduced worm burdens and a slightly elevated abomasal pH upon reinfection. In this study, we characterized the abomasal microbiota in response to reinfection using metagenomic tools. Compared to uninfected controls, infection did not induce a significant change in the microbial community composition in immune animals. 16S rRNA gene-based phylogenetic analysis identified 15 phyla in the bovine abomasal microbiota with Bacteroidetes (60.5%), Firmicutes (27.1%), Proteobacteria (7.2%), Spirochates (2.9%), and Fibrobacteres (1.5%) being the most predominant. The number of prokaryotic genera and operational taxonomic units (OTU) identified in the abomasal microbial community was 70.8±19.8 (mean ± SD) and 90.3±2.9, respectively. However, the core microbiome comprised of 32 genera and 72 OTU. Infection seemingly had a minimal impact on the abomasal microbial diversity at a genus level in immune animals. Proteins predicted from whole genome shotgun (WGS) DNA sequences were assigned to 5,408 Pfam and 3,381 COG families, demonstrating dazzling arrays of functional diversity in bovine abomasal microbial communities. However, none of COG functional classes were significantly impacted by infection. Our results demonstrate that immune animals may develop abilities to maintain proper stability of their abomasal microbial ecosystem. A minimal disruption in the bovine abomasal microbiota by reinfection may contribute equally to the restoration of gastric function in immune animals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.