ArticlePLoS genetics2011
Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.
Article in PLoS genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
48 citing papers in PubMed, 127 citations in OpenAlex.
- Increased triacylglycerol production in Rhodococcus opacus by overexpressing transcriptional regulators.Biotechnology for biofuels and bioproducts · 2024Article
- Fruit residues as substrates for single-cell oil production by Rhodococcus species: physiology and genomics of carbohydrate catabolism.World journal of microbiology & biotechnology · 2024Article
- Engineering ofHeliyon · 2023Article
- Development of Efficient Genome-Reduction Tool Based on Cre/Microorganisms · 2023Article
- The Carbon Source Effect on the Production of Ralstonia eutropha H16 and Proteomic Response Underlying Targeting the Bioconversion with Solar Fuels.Applied biochemistry and biotechnology · 2022Article
- Production of biopolymer precursors beta-alanine and L-lactic acid from COFrontiers in bioengineering and biotechnology · 2022Article
- Valorization of lignin components into gallate by integrated biological hydroxylation, O-demethylation, and aryl side-chain oxidation.Science advances · 2021Article
- Review
- Benchmarking DNA Extraction Methods for Phylogenomic Analysis of Sub-AntarcticMicroorganisms · 2021Article
- The Complete Genome Sequence and Structure of the OleaginousFrontiers in bioengineering and biotechnology · 2021Article
- Hydrogen oxidising bacteria for production of single-cell protein and other food and feed ingredients.Engineering biology · 2020Review
- The complete genome sequence of the nitrile biocatalyst Rhodocccus rhodochrous ATCC BAA-870.BMC genomics · 2020Article
- Insights into the Metabolism of OleaginousApplied and environmental microbiology · 2019Review
- Mechanism-Guided Design of Highly Efficient Protein Secretion and Lipid Conversion for Biomanufacturing and Biorefining.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- The pathogenic actinobacterium Rhodococcus equi: what's in a name?Molecular microbiology · 2019Review
- Engineering of an oleaginous bacterium for the production of fatty acids and fuels.Nature chemical biology · 2019Article
- Discovery of potential pathways for biological conversion of poplar wood into lipids by co-fermentation ofBiotechnology for biofuels · 2019Article
- Development ofBiotechnology for biofuels · 2019Review
- Production of single cell protein from agro-waste using Rhodococcus opacus.Journal of industrial microbiology & biotechnology · 2018Article
- Selection of stable reference genes for RT-qPCR in Rhodococcus opacus PD630.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 1 country.
Funding
Abstract
The Actinomycetales bacteria Rhodococcus opacus PD630 and Rhodococcus jostii RHA1 bioconvert a diverse range of organic substrates through lipid biosynthesis into large quantities of energy-rich triacylglycerols (TAGs). To describe the genetic basis of the Rhodococcus oleaginous metabolism, we sequenced and performed comparative analysis of the 9.27 Mb R. opacus PD630 genome. Metabolic-reconstruction assigned 2017 enzymatic reactions to the 8632 R. opacus PD630 genes we identified. Of these, 261 genes were implicated in the R. opacus PD630 TAGs cycle by metabolic reconstruction and gene family analysis. Rhodococcus synthesizes uncommon straight-chain odd-carbon fatty acids in high abundance and stores them as TAGs. We have identified these to be pentadecanoic, heptadecanoic, and cis-heptadecenoic acids. To identify bioconversion pathways, we screened R. opacus PD630, R. jostii RHA1, Ralstonia eutropha H16, and C. glutamicum 13032 for growth on 190 compounds. The results of the catabolic screen, phylogenetic analysis of the TAGs cycle enzymes, and metabolic product characterizations were integrated into a working model of prokaryotic oleaginy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.