ArticleNeuropsychiatric disease and treatment2011
Narcolepsy: a review.
Article in Neuropsychiatric disease and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Amphetamines in child medicine: a review of ClinicalTrials.gov.Frontiers in pharmacology · 2023Pooled it
- Moral decision making under modafinil: a randomized placebo-controlled double-blind crossover fMRI study.Psychopharmacology · 2019Trial
- Introduction to Pharmacogenomics: Role of the Histocompatibility and Immunogenetics Laboratory in Personalised Medicine-Current Status and Future Prospects.International journal of immunogenetics · 2026Review
- Pineal Region Tumors: Clinical Symptoms and Syndromes.Advances and technical standards in neurosurgery · 2026Review
- Making modafinil: Classification and serendipity in drug development.Social studies of science · 2025Article
- Dream Experiences During Intensive Care Unit Stay: Occurrence, Content, Vividness and Associated Factors.Nursing in critical care · 2025Article
- Chronic Methylphenidate Effects on Brain Gene Expression: An Exploratory Review.Psychology research and behavior management · 2024Review
- Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives.Journal of general internal medicine · 2023Article
- Narcolepsy-A Neuropathological Obscure Sleep Disorder: A Narrative Review of Current Literature.Brain sciences · 2022Review
- Differences in clinical and genetic characteristics between early- and late-onset narcolepsy in a Han Chinese cohort.Neural regeneration research · 2020Article
- On wakefulness fluctuations as a source of BOLD functional connectivity dynamics.Scientific reports · 2017Article
- The Humanistic and Economic Burden of Narcolepsy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
- Narcolepsy with Cataplexy in an Elderly Woman.Journal of general internal medicine · 2015Article
- Sleep disorders in multiple sclerosis. Review.Current neurology and neuroscience reports · 2015Review
- Case report of narcolepsy in a six-year-old child initially misdiagnosed as atypical epilepsy.Shanghai archives of psychiatry · 2014Article
- Cortical-subcortical interactions in hypersomnia disorders: mechanisms underlying cognitive and behavioral aspects of the sleep-wake cycle.Frontiers in neurology · 2014Review
- Animal models of sleep disorders.Comparative medicine · 2013Review
- Sleep paralysis in medieval Persia - the Hidayat of Akhawayni (?-983 AD).Neuropsychiatric disease and treatment · 2012Article
- Narcolepsy in Adolescence-A Missed Diagnosis: A Case Report.Innovations in clinical neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Narcolepsy is a lifelong sleep disorder characterized by a classic tetrad of excessive daytime sleepiness with irresistible sleep attacks, cataplexy (sudden bilateral loss of muscle tone), hypnagogic hallucination, and sleep paralysis. There are two distinct groups of patients, ie, those having narcolepsy with cataplexy and those having narcolepsy without cataplexy. Narcolepsy affects 0.05% of the population. It has a negative effect on the quality of life of its sufferers and can restrict them from certain careers and activities. There have been advances in the understanding of the pathogenesis of narcolepsy. It is thought that narcolepsy with cataplexy is secondary to loss of hypothalamic hypocretin neurons in those genetically predisposed to the disorder by possession of human leukocyte antigen DQB1*0602. The diagnostic criteria for narcolepsy are based on symptoms, laboratory sleep tests, and serum levels of hypocretin. There is no cure for narcolepsy, and the present mainstay of treatment is pharmacological treatment along with lifestyle changes. Some novel treatments are also being developed and tried. This article critically appraises the evidence for diagnosis and treatment of narcolepsy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.