ArticleInternational journal of nanomedicine2011
Adhesion of osteoblasts to a nanorough titanium implant surface.
Article in International journal of nanomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 192 citations in OpenAlex.
- Cells perceive the distribution differences of adhesion ligands and consequently establish cellular polarization to regulate osteogenic differentiation.Bioactive materials · 2026Article
- Polydopamine-doped PEDOT interfaces improve cell-electrode interactions and neural signal transmission.Scientific reports · 2026Article
- Simplified chemical deposition of CuJournal of materials science. Materials in medicine · 2025Article
- Biocompatibility Evaluation of Novel Experimental Titanium Alloys for Dental Implants.Dentistry journal · 2025Article
- Amino Silane High Positive Charge Layers: A Stable and Durable Alternative Based on Electrostatic Interactions for Titanium Applications, Combining Antimicrobial and Biological Properties.ACS applied bio materials · 2025Article
- Innovative Hydroxyapatite-Coated Titania Nanotubes for Dental Implant Surface Enhancement.Journal of clinical and experimental dentistry · 2025Article
- Eicosapentaenoic Acid and Docosahexaenoic Acid as an Antimicrobial Agent in Orthopedics-An In Vitro Study About the Race for Surface.Pathogens (Basel, Switzerland) · 2025Article
- Impact of plasma discharge pressure on implant surface properties and osteoblast activities in vacuum-assisted plasma treatment.Scientific reports · 2024Article
- Anisotropic patterns of nanospikes induces anti-biofouling and mechano-bactericidal effects of titanium nanosurfaces with electrical cue.Materials today. Bio · 2024Article
- A self-assembling graphene oxide coating for enhanced bactericidal and osteogenic properties of poly-ether-ether-ketone.Frontiers in bioengineering and biotechnology · 2024Article
- Surface Functionalization of Poly(lactic acid) via Deposition of Hydroxyapatite Monolayers for Biomedical Applications.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Effects of Cold Atmospheric Plasma Pre-Treatment of Titanium on the Biological Activity of Primary Human Gingival Fibroblasts.Biomedicines · 2023Article
- Advances in Multifunctional Bioactive Coatings for Metallic Bone Implants.Materials (Basel, Switzerland) · 2022Review
- Fabrication of Antibacterial TiOACS omega · 2022Article
- Effect of Currently Available Nanoparticle Synthesis Routes on Their Biocompatibility with Fibroblast Cell Lines.Molecules (Basel, Switzerland) · 2022Article
- The influence of nanotopography on cell behaviour through interactions with the extracellular matrix - A review.Bioactive materials · 2022Review
- Nanoporous Stainless Steel Materials for Body Implants-Review of Synthesizing Procedures.Nanomaterials (Basel, Switzerland) · 2022Review
- TiOACS applied materials & interfaces · 2022Article
- Titania nanospikes activate macrophage phagocytosis by ligand-independent contact stimulation.Scientific reports · 2022Article
- Bio-clickable mussel-inspired peptides improve titanium-based material osseointegration synergistically with immunopolarization-regulation.Bioactive materials · 2022Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work considers the adhesion of cells to a nanorough titanium implant surface with sharp edges. The basic assumption was that the attraction between the negatively charged titanium surface and a negatively charged osteoblast is mediated by charged proteins with a distinctive quadrupolar internal charge distribution. Similarly, cation-mediated attraction between fibronectin molecules and the titanium surface is expected to be more efficient for a high surface charge density, resulting in facilitated integrin mediated osteoblast adhesion. We suggest that osteoblasts are most strongly bound along the sharp convex edges or spikes of nanorough titanium surfaces where the magnitude of the negative surface charge density is the highest. It is therefore plausible that nanorough regions of titanium surfaces with sharp edges and spikes promote the adhesion of osteoblasts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.