ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2011
Effect of expanded US recommendations for seasonal influenza vaccination: comparison of two pediatric emergency departments in the United States and Canada.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Emergency department syndromic surveillance systems: a systematic review.BMC public health · 2020Pooled it
- Safety and tolerability of a 2009 trivalent inactivated split-virion influenza vaccine in infants, children and adolescents.Influenza and other respiratory viruses · 2013Trial
- [Does fear affect the willingness to be vaccinated? The influence of cognitive and affective aspects of risk perception during outbreaks].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2013Article
- Statement on Seasonal Influenza Vaccine for 2012-2013: Appendix I: New Evidence Review for Children 24 to 59 Months of Age: An Advisory Committee Statement (ACS) National Advisory Committee on Immunization (NACI).Canada communicable disease report = Releve des maladies transmissibles au Canada · 2012Article
- Modeling and statistical analysis of the spatio-temporal patterns of seasonal influenza in Israel.PloS one · 2012Article
- Targeting influenza vaccinations of children.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundStarting in the 2006/2007 influenza season, the US Advisory Committee on Immunization Practices expanded its recommendations for seasonal influenza vaccination to include healthy children aged 24-59 months. The parallel Canadian organization, the National Advisory Committee on Immunization, did not at that time issue a similar recommendation, thereby creating a natural experiment to evaluate the effect of the policy in the United States.
methodsWe examined data for 2000/2001 through 2008/2009 and estimated relative changes in visits to the emergency department for influenza-like illness at two pediatric hospitals, one in Boston, Massachusetts, and the other in Montréal, Quebec, following the US policy change. Models were adjusted for virologic factors, seasonal trends and all-cause utilization of the emergency department.
resultsOf 1 043 989 visits to the emergency departments of the two hospitals for any reason during the study period, 114 657 visits were related to influenza-like illness. Adjusted models estimated a 34% decline in rates of influenza-like illness among children two to four years old in the US hospital relative to the Canadian hospital (rate ratio 0.66, 95% confidence interval 0.58-0.75) following the 2006 policy change of the Advisory Committee on Immunization Practices. This was accompanied by more modest declines of 11% to 18% for the other age groups studied.
interpretationThe divergence in influenza rates among children in the US and Canadian sample populations after institution of the US policy to vaccinate children two to four years of age is evidence that the recommendation of the US Advisory Committee on Immunization Practices resulted in a reduction in influenza-related morbidity in the target group and may have indirectly affected other pediatric age groups. Provincial adoption of the 2010 recommendation of the National Advisory Committee on Immunization in Canada to vaccinate children two to four years of age might positively affect influenza morbidity in Canada.
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