ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2011
The meaning of a minuscule ribozyme.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
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- Coevolution of reproducers and replicators at the origin of life and the conditions for the origin of genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Pushing the Limits of Nucleic Acid Function.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Review
- Fitting the standard genetic code into its triplet table.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Kinetic Analysis Suggests Evolution of Ribosome Specificity in Modern Elongation Factor-Tus from "Generalist" Ancestors.Molecular biology and evolution · 2021Article
- Evolution of the Standard Genetic Code.Journal of molecular evolution · 2021Article
- Social Networking of Quasi-Species Consortia drive Virolution via Persistence.AIMS microbiology · 2021Review
- The 3-Minihelix tRNA Evolution Theorem.Journal of molecular evolution · 2020Article
- Evolution of Life on Earth: tRNA, Aminoacyl-tRNA Synthetases and the Genetic Code.Life (Basel, Switzerland) · 2020Review
- A tRNA- and Anticodon-Centric View of the Evolution of Aminoacyl-tRNA Synthetases, tRNAomes, and the Genetic Code.Life (Basel, Switzerland) · 2019Review
- Type-II tRNAs and Evolution of Translation Systems and the Genetic Code.International journal of molecular sciences · 2018Article
- In the Beginning was a Mutualism - On the Origin of Translation.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018Article
- Frozen Accident Pushing 50: Stereochemistry, Expansion, and Chance in the Evolution of the Genetic Code.Life (Basel, Switzerland) · 2017Article
- Self-Referential Encoding on Modules of Anticodon Pairs-Roots of the Biological Flow System.Life (Basel, Switzerland) · 2017Review
- Cross-backbone templating; ribodinucleotides made on poly(C).RNA (New York, N.Y.) · 2016Article
- Toward major evolutionary transitions theory 2.0.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- When Competing Viruses Unify: Evolution, Conservation, and Plasticity of Genetic Identities.Journal of molecular evolution · 2015Article
- A hypothesis about the origin of biology.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015Article
- What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental Attention.Life (Basel, Switzerland) · 2015Review
- How amino acids and peptides shaped the RNA world.Life (Basel, Switzerland) · 2015Review
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1 author.
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Abstract
The smallest ribozyme that carries out a complex group transfer is the sequence GUGGC-3', acting to aminoacylate GCCU-3' (and host a manifold of further reactions) in the presence of substrate PheAMP. Here, I describe the enzymatic rate, the characterization of about 20 aminoacyl-RNA and peptidyl-RNA products and the pathways of these GUGGC/GCCU reactions. Finally, the topic is evolution, and the potential implications of these data for the advent of translation itself.
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