Evidence map›Paper›PMID 21930392›Full record

ReviewSeminars in immunology2011

Factors and networks that underpin early hematopoiesis.

Elinore M Mercer, Yin C Lin, Cornelis Murre

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. A novel Boolean network inference strategy to model early hematopoiesis aging.Computational and structural biotechnology journal · 2023
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cutting Edge: Chromatin Accessibility Programs CD8 T Cell Memory.Journal of immunology (Baltimore, Md. : 1950) · 2017
    Article
  13. Review
  14. Article
  15. The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  16. New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elinore M MercerDepartment of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, United States. murre@biomail.ucsd.edu
Yin C Lin
Cornelis Murre

Funding

E2A as a Tumor SuppressorR01CA078384 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURRE, CORNELIS · 1999 to 2013
$5.4M
The 3D-Structures of the Immunoglobulin Heavy Chain LocusR01AI082850 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURRE, CORNELIS · 2009 to 2024
$5.4M
MOLECULAR BIOLOGICAL APPROACHES TO ENDOCRINOLOGYT32DK007541 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GAULTON, KYLE JEFFRIE, MAJITHIA, AMIT · 1987 to 2022
$4.5M
E PROTEIN AND B CELL DIFFERENTIATIONR37CA054198 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURRE, CORNELIS · 2001 to 2008
$3.5M
The role of E-proteins in B cell developmentR01CA054198 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURRE, CORNELIS · 1991 to 2013
$2.2M
Molecular Pathways to T-Lineage CommitmentR01AI062770 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURRE, CORNELIS · 2005 to 2009
$1.8M
The Molecular Mechanism for E2A Tumor SuppressorF32CA130276 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIN, YIN CHUN · 2007 to 2009
$154k
NCI NIH HHS 1F32CA130276NCI NIH HHS F32 CA130276NCI NIH HHS R01 CA054198NCI NIH HHS R01 CA078384NCI NIH HHS R37 CA054198NIAID NIH HHS R01 AI062770NIAID NIH HHS R01 AI082850NIDDK NIH HHS T32 DK007541PHS HHS RAI082850APHS HHS RCA078384C
6 · The paper itself

Abstract

Multiple trajectories have recently been described through which hematopoietic progenitor cells travel prior to becoming lineage-committed effectors. A wide spectrum of transcription factors has recently been identified that modulate developmental progression along such trajectories. Here we describe how distinct families of transcription factors act and are linked together to orchestrate early hematopoiesis.

Indexed as

Gene Expression Regulation, DevelopmentalCell LineageHematopoietic Stem CellsHumansModels, BiologicalTranscription FactorsTranscription Factors

Identifiers

PMID21930392
PMCPMC3217090

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.