Evidence map›Paper›PMID 2193005›Full record

ArticleHistochemistry1990

The antigen of bile canaliculi of the mouse hepatocyte: identification and ultrastructural localization.

N I Kuprina, V N Baranov, A K Yazova, T D Rudinskaya, M Escribano, J Cordier, A S Gleiberman, A I Goussev

Abstract read
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In one paragraph

Article in Histochemistry, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Expression of nestin-green fluorescent protein transgene marks oval cells in the adult liver.Developmental dynamics : an official publication of the American Association of Anatomists · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

N I KuprinaLaboratory of Immunochemistry, All-Union Cancer Research Center, Moscow, USSR.
V N Baranov
A K Yazova
T D Rudinskaya
M Escribano
J Cordier
A S Gleiberman
A I Goussev
Cancer Research Center · USCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AgB10 antigen of bile canaliculi of the mouse hepatocyte was identified using monoclonal antibodies. The Mr value of 116000 for AgB10 was measured by immunoblotting. The tissue localization of AgB10 was studied by light and electron microscopy using the immunoperoxidase technique. AgB10 was predominantly present on the microvillus membrane of bile canaliculi, the brush border of intestinal mucosa and apical surfaces of the epithelial cells in some other organs. A small amount of AgB10 was detected on the basolateral domain of the hepatocytes. AgB10 was specific for hepatocytes and was not found in the other cell types of the liver. In primary hepatocyte culture, AgB10 was localized on the surface of cells during the first 24 h, predominantly at the sites of cell-cell and cell-substratum contacts. After 48 h of culture AgB10 gradually disappeared from contacting cell surfaces and became concentrated only in the reconstituted bile canaliculi.

Indexed as

AnimalsAntibodies, MonoclonalAntigens, SurfaceBile CanaliculiBile Ducts, IntrahepaticCells, CulturedImmunoenzyme TechniquesIntestinesLiverMiceMice, Inbred C3HMice, Inbred C57BLMicroscopy, ElectronRatsTissue DistributionAntibodies, MonoclonalAntigens, Surface

Identifiers

PMID2193005
OpenAlexW2042693249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.