Evidence map›Paper›PMID 21929757›Full record

ArticleJournal of translational medicine2011

SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: online resources and useful tools - a compass in the land of biomarker discovery.

Davide Bedognetti, James M Balwit, Ena Wang, Mary L Disis, Cedrik M Britten, Lucia G Delogu, Sara Tomei, Bernard A Fox, Thomas F Gajewski, Francesco M Marincola and 1 more

Abstract read
In one paragraph

Article in Journal of translational medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Urinary miRNAs: Technical Updates.MicroRNA (Shariqah, United Arab Emirates) · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Preamble to the 2015 SITC immunotherapy biomarkers taskforce.Journal for immunotherapy of cancer · 2015
    Article
  12. Article
  13. Impact of carbon nanotubes and graphene on immune cells.Journal of translational medicine · 2014
    Review
  14. Article
  15. Article
  16. Article
  17. Ipilimumab: its potential in non-small cell lung cancer.Therapeutic advances in medical oncology · 2012
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Davide BedognettiSociety for Immunotherapy of Cancer, Milwaukee, WI, USA. Davide.Bedognetti@nih.gov.
James M Balwit
Ena Wang
Mary L Disis
Cedrik M Britten
Lucia G Delogu
Sara Tomei
Bernard A Fox
Thomas F Gajewski
Francesco M Marincola
Lisa H Butterfield

Funding

MECHANISMS THAT REGULATE TUMOR SPECIFIC IMMUNE RESPONSESR01CA080964 · NCI · PROVIDENCE PORTLAND MEDICAL CENTER · PI FOX, BERNARD A · 1999 to 2014
$3.3M
Immunogenetic Study of Infectious Diseases and CancerZIACL002118 · CLC · CLINICAL CENTER · PI MARINCOLA, FRANCESCO M · 2009 to 2012
$0k
NCI NIH HHS R01 CA080964
6 · The paper itself

Abstract

Recent positive clinical results in cancer immunotherapy point to the potential of immune-based strategies to provide effective treatment of a variety of cancers. In some patients, the responses to cancer immunotherapy are durable, dramatically extending survival. Extensive research efforts are being made to identify and validate biomarkers that can help identify subsets of cancer patients that will benefit most from these novel immunotherapies. In addition to the clear advantage of such predictive biomarkers, immune biomarkers are playing an important role in the development, clinical evaluation and monitoring of cancer immunotherapies. This Cancer Immunotherapy Resource Document, prepared by the Society for Immunotherapy of Cancer (SITC, formerly the International Society for Biological Therapy of Cancer, iSBTc), provides key references and online resources relevant to the discovery, evaluation and clinical application of immune biomarkers. These key resources were identified by experts in the field who are actively pursuing research in biomarker identification and validation. This organized collection of the most useful references, online resources and tools serves as a compass to guide discovery of biomarkers essential to advancing novel cancer immunotherapies.

Indexed as

DocumentationHealth ResourcesImmunotherapyInternetBiomarkers, TumorCongresses as TopicGuidelines as TopicHigh-Throughput Screening AssaysHumansNeoplasmsBiomarkers, Tumor

Identifiers

PMID21929757
PMCPMC3189883

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.