ArticlePlant cell reports2012
Enhanced extracellular production of trans-resveratrol in Vitis vinifera suspension cultured cells by using cyclodextrins and methyljasmonate.
Article in Plant cell reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 128 citations in OpenAlex.
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- Factors Affecting the Bioproduction of Resveratrol by Grapevine Cell Cultures under Elicitation.Biomolecules · 2023Article
- Biotechnological Approach to Increase Oxyresveratrol Production in Mulberry In Vitro Plants under Elicitation.Plants (Basel, Switzerland) · 2023Article
- The advent of plant cells in bioreactors.Frontiers in plant science · 2023Review
- Cyclodextrins Increase Triterpene Production inPlants (Basel, Switzerland) · 2022Article
- Phenylpropanoids in Silybum marianum cultures treated with cyclodextrins coated with magnetic nanoparticles.Applied microbiology and biotechnology · 2022Article
- Characterization of lipid droplets from a Taxus media cell suspension and their potential involvement in trafficking and secretion of paclitaxel.Plant cell reports · 2022Article
- Differential Response of Phenol Metabolism Associated with Antioxidative Network in Elicited Grapevine Suspension Cultured Cells under Saline Conditions.Antioxidants (Basel, Switzerland) · 2022Article
- The Role of Cyclodextrins in the Design and Development of Triterpene-Based Therapeutic Agents.International journal of molecular sciences · 2022Review
- Nucleoside 5'-Phosphoramidates Control the Phenylpropanoid Pathway inInternational journal of molecular sciences · 2021Article
- Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field.International journal of molecular sciences · 2021Review
- Biotic and Abiotic Elicitors of Stilbenes Production inPlants (Basel, Switzerland) · 2021Article
- Impact of Environmental Factors on Stilbene Biosynthesis.Plants (Basel, Switzerland) · 2021Review
- A Smart Strategy to ImprovePolymers · 2020Article
- Fungal Cell Wall and Methyl-β-Cyclodextrin Synergistically Enhance Paclitaxel Biosynthesis and Secretion in Corylus avellana Cell Suspension Culture.Scientific reports · 2020Article
- Optimize, Modulate, and Scale-up Resveratrol and Resveratrol Dimers Bioproduction inPlants (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this work, the effect of different inducing factors on trans-resveratrol extracellular production in Monastrell grapevine suspension cultured cells is evaluated. A detailed analysis provides the optimal concentrations of cyclodextrins, methyljasmonate and UV irradiation dosage, optimal cell density, elicitation time and sucrose content in the culture media. The results indicate that trans-resveratrol production decreases as the initial cell density increases for a constant elicitor concentration in Monastrell suspension cultured cells treated with cyclodextrins individually or in combination with methyljasmonate; the decrease observed in cell cultures elicited with cyclodextrins alone is far more drastic than those observed in the combined treatment. trans-Resveratrol extracellular production observed by the joint use of cyclodextrins and methyljasmonate (1,447.8 ± 60.4 μmol trans-resveratrol g(-1) dry weight) is lower when these chemical compounds are combined with UV light short exposure (669.9 ± 45.2 μmol trans-resveratrol g(-1) dry weight). Likewise, trans-resveratrol production is dependent on levels of sucrose in the elicitation medium with the maximal levels observed with 20 g l(-1) sucrose and the joint action of cyclodextrins and 100 μM methyljasmonate. The sucrose concentration did not seem to limit the process although it affects significantly the specific productivity since the lowest sucrose concentration is 10 g l(-1), the highest productivity is reached (100.7 ± 5.8 μmol trans-resveratrol g(-1) dry weight g(-1) sucrose) using cyclodextrins and 25 μM methyljasmonate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.