ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2012
Ethnic differences in composite indices of femoral neck strength.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Effect of vitamin D on bone strength in older African Americans: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Trial
- C-reactive protein, bone strength, and nine-year fracture risk: data from the Study of Women's Health Across the Nation (SWAN).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013Trial
- Trends in femoral neck fracture-related mortality in the United States: A nationwide retrospective study from 1999 to 2023.Medicine · 2026Article
- Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.Current osteoporosis reports · 2025Review
- Estimation of population affinity using proximal femoral measurements based on computed tomographic images in the Japanese and western Australian populations.International journal of legal medicine · 2024Article
- Osteoporosis and Fracture Risk among Older US Asian Adults.Current osteoporosis reports · 2023Review
- The menopause transition and women's health at midlife: a progress report from the Study of Women's Health Across the Nation (SWAN).Menopause (New York, N.Y.) · 2019 · on this mapReview
- Bone Health During the Menopause Transition and Beyond.Obstetrics and gynecology clinics of North America · 2018Review
- Cross-Calibration of GE Healthcare Lunar Prodigy and iDXA Dual-Energy X-Ray Densitometers for Bone Mineral Measurements.Journal of osteoporosis · 2016Article
- Article
- Adult bone strength of children from single-parent families: the Midlife in the United States Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Multisystem dysregulation and bone strength: findings from the study of midlife in the United States.The Journal of clinical endocrinology and metabolism · 2014Article
- Race/ethnic differences in associations between bone mineral density and fracture history in older men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Hip fractures in Hefei, China: the Hefei osteoporosis project.Journal of bone and mineral metabolism · 2014Article
- Physical activity as determinant of femoral neck strength relative to load in adult women: findings from the hip strength across the menopause transition study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- The Chinese skeleton: insights into microstructure that help to explain the epidemiology of fracture.Bone research · 2014Review
- Article
- Trajectories of femoral neck strength in relation to the final menstrual period in a multi-ethnic cohort.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
- Osteoporosis and treatments in Japan: management for preventing subsequent fractures.Journal of bone and mineral metabolism · 2013Review
- Ethnic variability in bone geometry as assessed by hip structure analysis: findings from the hip strength across the menopausal transition study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
unlabelledBone mineral density does not explain race/ethnicity differences in hip fracture risk. In this study, we demonstrated that race/ethnicity differences in composite hip strength indices were consistent with documented race/ethnicity differences in hip fracture risk, suggesting that unlike bone density, the composite indices may represent ethnicity-independent measures of bone strength.
introductionAfrican-American and Asian women have lower risks of hip fracture than Caucasian women, but such racial/ethnic variation in hip fracture risk cannot be explained by bone mineral density (BMD). The composite indices of femoral neck strength integrate femoral neck and body size with BMD and predict hip fracture risk in Caucasian women. We hypothesize that unlike race/ethnic differences in BMD, race/ethnic differences in the composite strength indices would be consistent with race/ethnic differences in hip fracture risk.
methodsWe studied a community-based sample of Caucasian (n = 968), African-American (n = 512), Chinese (n = 221), and Japanese (n = 239) women, premenopausal or in early perimenopause, from the Study of Women's Health Across the Nation.
resultsUnadjusted indices were similar in Caucasian and African-American women but higher in Asian women. After adjusting for age, body mass index, and menopause status, all three minority groups had higher composite strength indices than Caucasian women. Foreign-born Japanese women had higher unadjusted and adjusted composite strength indices than US-born Japanese women, but such differences by nativity were not observed in Chinese women.
conclusionWe concluded that composite strength indices have the potential to explain racial/ethnic differences in hip fracture risk, suggesting that composite strength indices may represent ethnicity-independent measures of bone strength. This contention needs to be verified by further research on the fracture predictive ability of composite strength indices in multi-ethnic longitudinal cohorts.
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