Evidence map›Paper›PMID 21927651›Full record

ArticleOncology reviews2011

A limited Review of Over Diagnosis Methods and Long Term Effects in Breast Cancer Screening.

Dongfeng Wu, Adriana Pérez

Abstract read
In one paragraph

Article in Oncology reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dongfeng WuDepartment of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40202, USA.
Adriana Pérez

Funding

Measurement Error, Nutrition and Breast/Colon CancerR37CA057030 · NCI · TEXAS A&M UNIVERSITY SYSTEM · PI CARROLL, RAYMOND J. · 2005 to 2014
$3.3M
Measurement Error, Nutrition, Physical Activity and CancerU01CA057030 · NCI · TEXAS A&M UNIVERSITY · PI CARROLL, RAYMOND J. · 2015 to 2019
$2.8M
MEASUREMENT ERROR, NUTRITION AND BREAST/COLON CANCERR01CA057030 · NCI · TEXAS A&M UNIVERSITY SYSTEM · PI CARROLL, RAYMOND J. · 1992 to 2004
$1.3M
NCI NIH HHS R37 CA057030
6 · The paper itself

Abstract

Breast cancer screening programs have been effective in detecting tumors prior to symptoms. Recently, there has been concern over the issue of over-diagnosis, that is, diagnosis of a breast cancer that does not manifest prior to death. Estimates for over-diagnosis vary, ranging from 7% to 52%. This variability may be due partially to issues associated with bias and/or incorrect inferences associated with the lack of probability modeling. A critical issue is how to evaluate the long-term effects due to continued screening. Participants in a periodic screening program can be classified into four mutually exclusive groups depending on whether individuals are diagnosed and whether their symptoms appear prior to death: True-early-detection; No-early-detection; Over-diagnosis; and Not-so-necessary. All initially superficially healthy people will eventually fall into one of these four categories. This manuscript reviews the major methodologies associated with the over-diagnosis and long-term effects of breast cancer screening.

Identifiers

PMID21927651
PMCPMC3171741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.