ArticleNature genetics2011
Bayesian inference of ancient human demography from individual genome sequences.
Article in Nature genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 287 papers.
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Who cites it
287 citing papers in PubMed.
- Evolutionary history of disease-susceptibility loci identified in longitudinal exome-wide association studies.Molecular genetics & genomic medicine · 2019Trial
- Genetics and genomics of hybridization.Nature reviews. Genetics · 2026Review
- Taxonomic inflation in fish systematics: A critical review with illustrative evidence assessment and integrative case study of the Salmo trutta Complex.Journal of fish biology · 2026Review
- Targeted chromosomal sequencing of wild bonobos identifies a genetically distinct subpopulation east of the Lomami river.Genome biology · 2026Article
- ERICA-trio: an outgroup-free deep learning method for topology inference and introgression detection.Briefings in bioinformatics · 2026Article
- A transparent and generalizable deep-learning framework for genomic ancestry prediction.American journal of human genetics · 2026Article
- FRAME: Fine-Resolution Asymmetric Migration Estimation.Nature communications · 2026Article
- Revisiting the African mtDNA landscape through complete mitochondrial genomes.Communications biology · 2026Article
- Scaling up Bayesian population phylogenomics through virtual dimension reduction.Nature communications · 2026Article
- Genomics of rafting crustaceans reveals adaptation to climate change in tropical oceans.Nature communications · 2026Article
- Article
- Targeted Chromosomal Sequencing of Wild Bonobos Identifies a Genetically Distinct Subpopulation East of the Lomami River.bioRxiv : the preprint server for biology · 2026Article
- On the robustness of Bayesian inference of gene flow to intragenic recombination and natural selection.Molecular biology and evolution · 2026Article
- Article
- A curated dataset of great ape genome diversity.Scientific data · 2025Article
- Accounting for gene flow from unsampled ghost populations while estimating evolutionary history.G3 (Bethesda, Md.) · 2025Article
- Ancient genomes provide evidence of demographic shift to Slavic-associated groups in Moravia.Genome biology · 2025Article
- The power of coalescent methods for inferring recent and ancient gene flow in endangered Bactrian camels.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Impact of Sequencing and Genotyping Errors on Bayesian Analysis of Genomic Data under the Multispecies Coalescent Model.Molecular biology and evolution · 2025Article
- Spatiotemporal Dynamics of Non-Ecological Speciation in Rubyspot Damselflies (Hetaerina spp.).Molecular ecology · 2025Article
227 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
Whole-genome sequences provide a rich source of information about human evolution. Here we describe an effort to estimate key evolutionary parameters based on the whole-genome sequences of six individuals from diverse human populations. We used a Bayesian, coalescent-based approach to obtain information about ancestral population sizes, divergence times and migration rates from inferred genealogies at many neutrally evolving loci across the genome. We introduce new methods for accommodating gene flow between populations and integrating over possible phasings of diploid genotypes. We also describe a custom pipeline for genotype inference to mitigate biases from heterogeneous sequencing technologies and coverage levels. Our analysis indicates that the San population of southern Africa diverged from other human populations approximately 108-157 thousand years ago, that Eurasians diverged from an ancestral African population 38-64 thousand years ago, and that the effective population size of the ancestors of all modern humans was ∼9,000.
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