Trial reportCritical care medicine2012
A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions.
Trial report in Critical care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Endotracheal Tubes Cleaned With a Novel Mechanism for Secretions Removal
Evaluation of a Closed Suction System to Remove Secretions From the Endotracheal Tube: a Randomized Trial
Who cites it
25 citing papers in PubMed, 81 citations in OpenAlex.
- Evaluation of a Closed Suction System With Integrated Tube-Scraping Technology.Respiratory care · 2023Trial
- Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2026Article
- Endotracheal Tube Cleaning Devices: A Means But Not a Solution.Respiratory care · 2023Article
- Airway and Respiratory Devices in the Prevention of Ventilator-Associated Pneumonia.Medicina (Kaunas, Lithuania) · 2023Review
- The Current Knowledge on the Pathogenesis of Tissue and Medical Device-Related Biofilm Infections.Microorganisms · 2022Article
- Bacteriophage Cocktail-Mediated Inhibition ofAntibiotics (Basel, Switzerland) · 2021Article
- Evaluation of a novel endotracheal tube suctioning system incorporating an inflatable sweeper.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2021Article
- Selective digestive decontamination solution used as "lock therapy" prevents and eradicates bacterial biofilm in an in vitro bench-top model.Annals of clinical microbiology and antimicrobials · 2020Article
- Biofilm formation on three different endotracheal tubes: a prospective clinical trial.Critical care (London, England) · 2020Observational
- Strategies for measuring airway mucus and mucins.Respiratory research · 2019Review
- Comparative efficacy of linezolid and vancomycin for endotracheal tube MRSA biofilms from ICU patients.Critical care (London, England) · 2019Observational
- Understanding Biofilms and Novel Approaches to the Diagnosis, Prevention, and Treatment of Medical Device-Associated Infections.Infectious disease clinics of North America · 2018Review
- Assessment of in vivo versus in vitro biofilm formation of clinical methicillin-resistant Staphylococcus aureus isolates from endotracheal tubes.Scientific reports · 2018Article
- Article
- Article
- Micropatterned Endotracheal Tubes Reduce Secretion-Related Lumen Occlusion.Annals of biomedical engineering · 2016Article
- The use of a novel cleaning closed suction system reduces the volume of secretions within the endotracheal tube as assessed by micro-computed tomography: a randomized clinical trial.Annals of intensive care · 2015Article
- Endotracheal tube biofilm translocation in the lateral Trendelenburg position.Critical care (London, England) · 2015Article
- Measurement of endotracheal tube secretions volume by micro computed tomography (MicroCT) scan: an experimental and clinical study.BMC anesthesiology · 2014Observational
- [Ventilator-associated pneumonia].Der Internist · 2013Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objective: We evaluated a new device designed to clean the endotracheal tube in mechanically ventilated patients, the Mucus Shaver.
design: Prospective, randomized trial.
setting: University hospital intensive care unit. PATIENTS: : We enrolled 24 patients expected to remain ventilated for >72 hrs.
interventions: The Mucus Shaver is a concentric inflatable catheter for the removal of mucus and secretions from the interior surface of the endotracheal tube. The Mucus Shaver is advanced to the distal endotracheal tube tip, inflated, and subsequently withdrawn over a period of 3-5 secs. Patients were prospectively randomized within 2 hrs of intubation to receive standard endotracheal tube suctioning treatment or standard suctioning plus Mucus Shaver use until extubation. MEASUREMENTS AND MAIN
results: During the study period, demographic data, recent medical history, adverse events, and staff evaluation of the Mucus Shaver were recorded. At extubation, each endotracheal tube was removed, cultured, and analyzed by scanning electron microscopy. Twelve patients were assigned to the study group and 12 were assigned to the control group. No adverse events related to the use of the Mucus Shaver were observed. At extubation, only one endotracheal tube from the Mucus Shaver group was colonized, whereas in the control group ten endotracheal tubes were colonized (8% vs. 83%; p < .001). Scanning electron microscopy showed little secretions on the endotracheal tubes from the study group, whereas thick bacterial deposits were present on all the endotracheal tubes from the control group (p < .001 by Fisher exact test, using a maximum biofilm thickness of 30 μm as cut-off). The nursing staff was satisfied by the overall safety, feasibility, and efficacy of the Mucus Shaver.
conclusions: The Mucus Shaver is a safe, feasible, and efficient device for endotracheal tube cleaning in the clinical setting. The Mucus Shaver is helpful in preventing endotracheal tube colonization by potentially harmful microorganisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.