ArticleGenetics2011
Interactions among flower-size QTL of Mimulus guttatus are abundant but highly variable in nature.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- PeCIN8 expression correlates with flower size and resistance to yellow leaf disease in Phalaenopsis orchids.BMC plant biology · 2023Article
- How early does the selfing syndrome arise? Associations between selfing ability and flower size within populations of the mixed-mater Collinsia verna.American journal of botany · 2022Article
- Experimental migration upward in elevation is associated with strong selection on life history traits.Ecology and evolution · 2020Article
- Article
- Pervasive antagonistic interactions among hybrid incompatibility loci.PLoS genetics · 2017Article
- Article
- Size control in plants--lessons from leaves and flowers.Cold Spring Harbor perspectives in biology · 2015Review
- Naturally segregating loci exhibit epistasis for fitness.Biology letters · 2015Article
- Epistasis Is a Major Determinant of the Additive Genetic Variance in Mimulus guttatus.PLoS genetics · 2015Article
- A quantitative framework for flower phenotyping in cultivated carnation (Dianthus caryophyllus L.).PloS one · 2013Article
- Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus.Molecular ecology · 2012Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The frequency and character of interactions among genes influencing complex traits remain unknown. Our ignorance is most acute for segregating variation within natural populations, the epistasis most relevant for quantitative trait evolution. Here, we report a comprehensive survey of interactions among a defined set of flower-size QTL: loci polymorphic within a single natural population of yellow monkeyflower (Mimulus guttatus). We find that epistasis is typical. Observed phenotypes routinely differ from those predicted on the basis of direct allelic affects in the isogenic background, although the direction of deviations is highly variable. Across QTL pairs, there are significantly positive and negative interactions for every trait. Across traits, specific locus pairs routinely exhibit both positive and negative interactions. There was a tendency for negative epistasis to accompany positive direct effects and vice versa for the trait of corolla width, which may be due, at least in part, to the fact that QTL were identified from their direct effects on this trait.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.