ArticleApplied and environmental microbiology2011
Increased persistence of Salmonella enterica serovar Typhi in the presence of Acanthamoeba castellanii.
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- The Phase-Specific Dynamics in Gene Expression of Salmonella Typhimurium During Acanthamoeba castellanii Infection.Current microbiology · 2025Article
- Article
- First Report of Isolation and Characterization of Acanthamoeba spp. from the Milk Used for Calf Feeding.Acta parasitologica · 2024Article
- Typhoidal salmonella disease in Mukuru informal settlement, Nairobi Kenya; carriage, diversity, and antimicrobial resistant genes.PloS one · 2024Article
- Biofilm formation of Salmonella enterica serovar Enteritidis cocultured with Acanthamoeba castellanii responds to nutrient availability.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Spatial and Genomic Data to Characterize Endemic Typhoid Transmission.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Exploring the nature of interaction between shiga toxin producingFrontiers in cellular and infection microbiology · 2022Article
- Cappable-Seq Reveals Specific Patterns of Metabolism and Virulence forInternational journal of molecular sciences · 2021Article
- Evaluation of the occurrence of pathogenic free-living amoeba and bacteria in 20 public indoor swimming pool facilities.MicrobiologyOpen · 2021Article
- Reviving the "Moore Swab": a Classic Environmental Surveillance Tool Involving Filtration of Flowing Surface Water and Sewage Water To Recover TyphoidalApplied and environmental microbiology · 2020Review
- Combining Whole-Genome Sequencing and Multimodel Phenotyping To Identify Genetic Predictors ofmSphere · 2020Article
- Type 1 Fimbriae and Motility Play a Pivotal Role During Interactions of Salmonella typhimurium with Acanthamoeba castellanii (T4 Genotype).Current microbiology · 2020Article
- Molecular Characteristics and Zoonotic Potential ofFrontiers in microbiology · 2020Article
- Co-culture models illustrate the digestion of Gemmata spp. by phagocytes.Scientific reports · 2018Article
- The cellulose synthase BcsA plays a role in interactions of Salmonella typhimurium with Acanthamoeba castellanii genotype T4.Parasitology research · 2018Article
- Presence and Persistence ofFrontiers in public health · 2018Review
- Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process.Biology · 2016Review
- Yersinia pseudotuberculosis IP32953 survives and replicates in trophozoites and persists in cysts of Acanthamoeba castellanii.FEMS microbiology letters · 2015Article
- Interactions between Human Norovirus Surrogates and Acanthamoeba spp.Applied and environmental microbiology · 2015Article
- Monitoring F1651 P-like fimbria expression at the single-cell level reveals a highly heterogeneous phenotype.Infection and immunity · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonella enterica serovar Typhi (S. Typhi) is the etiological agent of the systemic disease typhoid fever. Transmission occurs via ingestion of contaminated food or water. S. Typhi is specific to humans, and no animal or environmental reservoirs are known. As the free-living amoeba Acanthamoeba castellanii is an environmental host for many pathogenic bacteria, this study investigates interactions between S. Typhi and A. castellanii by using cocultures. Growth of both organisms was estimated by cell count, viable count, flow cytometry, and fluorescence microscopy. Results indicate that S. Typhi can survive at least 3 weeks when grown with A. castellanii, as opposed to less than 10 days when grown as singly cultured bacteria under the same conditions. Interestingly, growth rates of amoebae after 14 days were similar in cocultures or when amoebae were singly cultured, suggesting that S. Typhi is not cytotoxic to A. castellanii. Bacteria surviving in coculture were not intracellular and did not require a physical contact with amoebae for their survival. These results suggest that S. Typhi may have a selective advantage when it is associated with A. castellanii and that amoebae may contribute to S. Typhi persistence in the environment.
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