ArticleJournal of experimental botany2012
RNAi-mediated disruption of squalene synthase improves drought tolerance and yield in rice.
Article in Journal of experimental botany, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 128 citations in OpenAlex.
- Molecular and Genetic Regulation of Crop Root System Architecture in Drought Resilience.Plants (Basel, Switzerland) · 2026Review
- Divergent physiological strategies distinguish tolerant and plastic genotypes in elite Australian rice lines under limited irrigation.Frontiers in plant science · 2026Article
- Advances in RNA Interference for Plant Functional Genomics: Unveiling Traits, Mechanisms, and Future Directions.Applied biochemistry and biotechnology · 2024Review
- Integrating physiological and multi-omics methods to elucidate heat stress tolerance for sustainable rice production.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Tools and Techniques to Accelerate Crop Breeding.Plants (Basel, Switzerland) · 2024Review
- Genotype-Dependent Response of Root Microbiota and Leaf Metabolism in Olive Seedlings Subjected to Drought Stress.Plants (Basel, Switzerland) · 2024Article
- Functional Characterization of Four Olive Squalene Synthases with Respect to the Squalene Content of the Virgin Olive Oil.Journal of agricultural and food chemistry · 2023Article
- The Identification ofMolecules (Basel, Switzerland) · 2023Article
- Downregulation of Squalene Synthase Broadly Impacts Isoprenoid Biosynthesis in Guayule.Metabolites · 2022Article
- Inactivating transcription factor OsWRKY5 enhances drought tolerance through abscisic acid signaling pathways.Plant physiology · 2022Article
- Biological Parts for Engineering Abiotic Stress Tolerance in Plants.Biodesign research · 2022Review
- Identification of Candidate Genes for Salinity and Anaerobic Tolerance at the Germination Stage in Rice by Genome-Wide Association Analyses.Frontiers in genetics · 2022Article
- RNA Interference and CRISPR/Cas Gene Editing for Crop Improvement: Paradigm Shift towards Sustainable Agriculture.Plants (Basel, Switzerland) · 2021Review
- Improving Performance of Salt-Grown Crops by Exogenous Application of Plant Growth Regulators.Biomolecules · 2021Review
- Linkage analysis, GWAS, transcriptome analysis to identify candidate genes for rice seedlings in response to high temperature stress.BMC plant biology · 2021Article
- Physiological and Multi-Omics Approaches for Explaining Drought Stress Tolerance and Supporting Sustainable Production of Rice.Frontiers in plant science · 2021Review
- Genome-Wide Association Study of Rice Rooting Ability at the Seedling Stage.Rice (New York, N.Y.) · 2020Article
- Expression of the CCCH-tandem zinc finger protein gene OsTZF5 under a stress-inducible promoter mitigates the effect of drought stress on rice grain yield under field conditions.Plant biotechnology journal · 2020Article
- AtJ3, a specific HSP40 protein, mediates protein farnesylation-dependent response to heat stress in Arabidopsis.Planta · 2019Article
- Probing the function of protein farnesyltransferase in Tripterygium wilfordii.Plant cell reports · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About one-third of the world's rice area is in rain-fed lowlands and most are prone to water shortage. The identification of genes imparting tolerance to drought in the model cereal plant, rice, is an attractive strategy to engineer improved drought tolerance not only rice but other cereals as well. It is demonstrated that RNAi-mediated disruption of a rice farnesyltransferase/squalene synthase (SQS) by maize squalene synthase improves drought tolerance at both the vegetative and reproductive stages. Twenty-day-old seedlings of wild type (Nipponbare) and seven independent events of transgenic RNAi lines showed no difference in morphology. When subjected to water stress for a period of 32 d under growth chamber conditions, transgenic positives showed delayed wilting, conserved more soil water, and improved recovery. When five independent events along with wild-type plants were subjected to drought at the reproductive stage under greenhouse conditions, the transgenic plants lost water more slowly compared with the wild type, through reduced stomatal conductance and the retention of high leaf relative water content (RWC). After 28 d of slow progressive soil drying, transgenic plants recovered better and flowered earlier than wild-type plants. The yield of water-stressed transgenic positive plants ranged from 14-39% higher than wild-type plants. When grown in plates with Yoshida's nutrient solution with 1.2% agar, transgenic positives from three independent events showed increased root length and an enhanced number of lateral roots. The RNAi-mediated inactivation produced reduced stomatal conductance and subsequent drought tolerance.
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