Evidence map›Paper›PMID 21926086›Full record

ArticleJournal of molecular cell biology2011

MADM gives new insights into gliomagenesis.

Liang Lei, Peter Canoll

Abstract read
In one paragraph

Article in Journal of molecular cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liang LeiDepartment of Pathology and Cell Biology, Columbia University, NY 10032, USA.
Peter Canoll

Funding

The Role of White Matter Progenitors in Glioma Formation and ProgressionR01NS066955 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANOLL, PETER · 2010 to 2014
$1.7M
NINDS NIH HHS R01 NS066955
6 · The paper itself

Abstract

In their recent paper, Liu et al. (2011) make use of an elegant genetic mouse model to study the formation of malignant brain tumors. Their findings add strong support to the growing body of evidence from several labs showing that some gliomas arise from oligodendrocyte precursor cells (OPCs). They also provide new insights, and raise new questions, regarding where, when, and how malignant gliomas form.

Indexed as

Cell Transformation, NeoplasticAnimalsBrain NeoplasmsGliomaHumansMiceMosaicismOligodendrogliaStem Cells

Identifiers

PMID21926086
PMCPMC3695595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.