Evidence map›Paper›PMID 21925897›Full record

ReviewSeminars in immunology2012

Autoantibody formation in human and rat studies of chronic rejection and primary graft dysfunction.

David S Wilkes

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. Update on lung transplantation: programmes, patients and prospects.European respiratory review : an official journal of the European Respiratory Society · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David S WilkesCenter for Immunobiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. dwilkes@iupui.edu
Indiana University – Purdue University Indianapolis · US

Funding

Transgenic Mouse CoreP01AI084853 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI WILKES, DAVID S · 2010 to 2014
$7.7M
Type V Collagen Prevents Lung Allograft RejectionR01HL067177 · NHLBI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WILKES, DAVID S · 2001 to 2011
$3.7M
Role of anti-Col (V) immunity in primary graft dysfunctionR01HL096845 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D, WILKES, DAVID S · 2010 to 2013
$2.2M
NHLBI NIH HHS HL067177NHLBI NIH HHS R01 HL067177NHLBI NIH HHS R01 HL096845NHLBI NIH HHS R01HL096845NIAID NIH HHS 1P01AI084853NIAID NIH HHS P01 AI084853
6 · The paper itself

Abstract

Lung transplantation is considered a definitive treatment for many lung diseases. However, rejection and other pathologic entities are major causes of morbidity and mortality for lung transplant recipients. Primary graft dysfunction (PGD) and obliterative bronchiolitis (OB) are the leading causes of early and late mortality, respectively. While the immune basis of PGD has not been clearly defined, evidence is emerging about roles for autoantibodies in this process. Similarly, the pathogenesis of OB has been linked recently to autoimmunity. This review will highlight the current understanding of autoantibodies in PGD and OB post lung transplantation.

Indexed as

AnimalsAutoantibodiesBronchiolitis ObliteransChronic DiseaseDisease Models, AnimalGraft RejectionHumansLung TransplantationMicePrimary Graft DysfunctionRatsAutoantibodies

Identifiers

PMID21925897
PMCPMC3873136
OpenAlexW2016236633

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.