Evidence map›Paper›PMID 21925739›Full record

ArticleJournal of affective disorders2012

RETRACTED: Dysregulated glutamate and dopamine transporters in postmortem frontal cortex from bipolar and schizophrenic patients.

Jagadeesh Sridhara Rao, Matthew Kellom, Edmund Arthur Reese, Stanley Isaac Rapoport, Hyung-Wook Kim

RetractedOpen access · greenAbstract readRetracted Publication
In one paragraph

Article in Journal of affective disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Astroglial correlates of neuropsychiatric disease: From astrocytopathy to astrogliosis.Progress in neuro-psychopharmacology & biological psychiatry · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Animal models for bipolar disorder: from bedside to the cage.International journal of bipolar disorders · 2017
    Review
  12. Review
  13. DifferentialFrontiers in cellular neuroscience · 2017
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Modeling mania in preclinical settings: A comprehensive review.Progress in neuro-psychopharmacology & biological psychiatry · 2016
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jagadeesh Sridhara RaoBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States. Electronic address: jrao@grc.nia.nih.gov.
Matthew KellomBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States.
Edmund Arthur ReeseBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States.
Stanley Isaac RapoportBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States.
Hyung-Wook KimBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States.
Institute on Aging · USNational Institute on Aging · USNational Institutes of Health · US

Funding

A Natonal Resource for Postmortem Brain ResearchR24MH068855 · NIMH · MC LEAN HOSPITAL (BELMONT, MA) · PI BENES, FRANCINE M. · 2003 to 2012
$14.8M
Texas Tech Center for Translational Research and Rural Health - Research Capacity CoreU54MD020892 · NIMHD · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI Lance R. McMahon · 2026 to 2026
$10.0M
Lipids in Human Brain DiseaseZIAAG000428 · NIA · NATIONAL INSTITUTE ON AGING · PI RAPOPORT, STANLEY I. · 2009 to 2016
$2.6M
Intramural NIH HHS Z99 AG999999NIA NIH HHS R99 AG999999NIMHD NIH HHS U54 MD020892NIMH NIH HHS R24 MH068855
6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of The National Institutes of Health has found that the first author, Dr. Jagadeesh S. Rao engaged in research misconduct by falsifying data in “Dysregulated glutamate and dopamine transporters in postmortem frontal cortex from bipolar and schizophrenic patients”. Rao JS, Kellom M, Reese EA, Rapoport SI, Kim HW. J. Affect Disord. 136(1–2):63–71. 2012. Data in Figures 2A, 2B, 3A, 3B and 4A were falsified.

Indexed as

Amino Acid Transport System X-AGAutopsyBipolar DisorderDopamine Plasma Membrane Transport ProteinsFemaleFrontal LobeGlutamate Plasma Membrane Transport ProteinsHumansMaleMiddle AgedSchizophreniaSerotonin Plasma Membrane Transport ProteinsAmino Acid Transport System X-AGDopamine Plasma Membrane Transport ProteinsGlutamate Plasma Membrane Transport ProteinsSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID21925739
PMCPMC3254216
OpenAlexW2019921771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.