Evidence map›Paper›PMID 21925611›Full record

ArticleNeuroImage2012

Improving measurement of functional connectivity through decreasing partial volume effects at 7 T.

Allen T Newton, Baxter P Rogers, John C Gore, Victoria L Morgan

Abstract read
In one paragraph

Article in NeuroImage, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Phenotyping Superagers Using Resting-State fMRI.AJNR. American journal of neuroradiology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Evaluation of statistical inference on empirical resting state fMRI.IEEE transactions on bio-medical engineering · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allen T NewtonVanderbilt University Institute of Imaging Science, Department of Radiology and Radiological Science, 1161 21st Avenue South, Medical Center North, AA-1105, Nashville, TN 37232-2310, USA. Allen.t.newton@vanderbilt.edu
Baxter P Rogers
John C Gore
Victoria L Morgan

Funding

Integrated Imaging of Brain Function at 7 TeslaR01EB000461 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2002 to 2012
$9.4M
Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
7 Tesla Human Magnetic Resonance Imaging and Spectroscopy SystemS10RR023047 · NCRR · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2007 to 2007
$2.0M
Predoctoral Training Program in Biomedical ImagingT32EB003817 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2004 to 2008
$1.3M
NCRR NIH HHS S10 RR023047NIBIB NIH HHS R01 EB000461NIBIB NIH HHS R01 EB00461NIBIB NIH HHS T32 EB001628NIBIB NIH HHS T32 EB003817NIBIB NIH HHS T32EB03817
6 · The paper itself

Abstract

Several applications of fMRI at high field have taken advantage of the increased BOLD contrast to increase spatial resolution, but the potential benefits of higher fields for detecting and analyzing functional connectivity have largely been unexplored. We measured the influence of spatial resolution at 7 T on estimates of functional connectivity through decreased partial volume averaging. Ten subjects were imaged at 7 T with a range of spatial resolutions (1×1×2 mm to 3×3×2 mm) during performance of a finger tapping task and in the resting state. We found that resting state correlations within the sensory-motor system increase as voxel dimensions decreased from 3×3×2 mm to 1×1×2 mm, whereas connectivity to other brain regions was unaffected. This improvement occurred even as overall signal to noise ratios decrease. Our data suggest that this increase may be due to decreased partial volume averaging, and that functional connectivity within the primary seed region is heterogeneous on the scale of single voxels.

Indexed as

AlgorithmsAnalysis of VarianceArtifactsBrain MappingEfferent PathwaysFingersHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementNeural PathwaysNormal DistributionOxygenPsychomotor PerformanceRestSignal-To-Noise RatioOxygen

Identifiers

PMID21925611
PMCPMC3254819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.