ArticleCell2011
Synaptic plasticity of feeding circuits: hormones and hysteresis.
Article in Cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular Diseases.Cells · 2023Review
- Fasting inhibits excitatory synaptic input on paraventricular oxytocin neuronsFrontiers in nutrition · 2022Article
- FGF1 - a new weapon to control type 2 diabetes mellitus.Nature reviews. Endocrinology · 2017Review
- Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.eLife · 2017Article
- Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight.Cell metabolism · 2017Article
- Article
- Review
- Sex differences in feeding behavior in rats: the relationship with neuronal activation in the hypothalamus.Frontiers in neuroscience · 2015Review
- Control of obesity and glucose intolerance via building neural stem cells in the hypothalamus.Molecular metabolism · 2014Article
- Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons.Nature reviews. Drug discovery · 2012Review
- Alteration of hypothalamic cellular dynamics in obesity.The Journal of clinical investigation · 2012Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The drive to eat is controlled by neuronal circuits in the hypothalamus that respond to hormones signaling hunger or satiety. In this issue of Cell, Yang et al. (2011) reveal an AMPK-dependent synaptic pathway that sustains excitatory stimulation of the NPY/AgRP neurons that promote feeding behavior until satiety signals kick in.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.