ReviewAdvances in genetics2011
The genetics of circadian rhythms in Neurospora.
Review in Advances in genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 39 citations in OpenAlex.
- Identification of Circadian Clock Homologs and Their Rhythmic Expression Differences Among Mating-Type Strains inJournal of fungi (Basel, Switzerland) · 2026Article
- Rhythmicity of TOR (Target of Rapamycin) Activity Supports Circadian Function inJournal of biological rhythms · 2026Article
- Individual peroxiredoxin or Tor pathway components are not required for circadian clock function in Neurospora crassa.Fungal biology · 2025Article
- Circadian rhythms: pervasive, and often times evasive.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- The Cryptochrome CryA Regulates Lipid Droplet Accumulation, Conidiation, and Trap Formation via Responses to Light inJournal of fungi (Basel, Switzerland) · 2024Article
- The Case for the Target of Rapamycin Pathway as a Candidate Circadian Oscillator.International journal of molecular sciences · 2023Review
- An Anatomy of Fungal Eye: Fungal Photoreceptors and Signalling Mechanisms.Journal of fungi (Basel, Switzerland) · 2023Review
- Differential regulation of phosphorylation, structure, and stability of circadian clock protein FRQ isoforms.The Journal of biological chemistry · 2023Article
- Circadian oscillations ineLife · 2022Article
- Shared Components of the FRQ-Less Oscillator and TOR Pathway Maintain Rhythmicity inJournal of biological rhythms · 2021Article
- A global search for novel transcription factors impacting the Neurospora crassa circadian clock.G3 (Bethesda, Md.) · 2021Article
- A component of the TOR (Target Of Rapamycin) nutrient-sensing pathway plays a role in circadian rhythmicity in Neurospora crassa.PLoS genetics · 2018Article
- Making Time: Conservation of Biological Clocks from Fungi to Animals.Microbiology spectrum · 2017Review
- A Ras GTPase associated protein is involved in the phototropic and circadian photobiology responses in fungi.Scientific reports · 2017Article
- CGDB: a database of circadian genes in eukaryotes.Nucleic acids research · 2017Article
- Natural Variation of the Circadian Clock in Neurospora.Advances in genetics · 2017Review
- Analysis of Circadian Rhythms in the Basal Filamentous Ascomycete Pyronema confluens.G3 (Bethesda, Md.) · 2015Article
- Quantitative Circadian Phosphoproteomic Analysis of Arabidopsis Reveals Extensive Clock Control of Key Components in Physiological, Metabolic, and Signaling Pathways.Molecular & cellular proteomics : MCP · 2015Article
- Suppressing the Neurospora crassa circadian clock while maintaining light responsiveness in continuous stirred tank reactors.Scientific reports · 2015Article
- Mechanism of the Neurospora circadian clock, a FREQUENCY-centric view.Biochemistry · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
This chapter describes our current understanding of the genetics of the Neurospora clock and summarizes the important findings in this area in the past decade. Neurospora is the most intensively studied clock system, and the reasons for this are listed. A discussion of the genetic interactions between clock mutants is included, highlighting the utility of dissecting complex mechanisms by genetic means. The molecular details of the Neurospora circadian clock mechanism are described, as well as the mutations that affect the key clock proteins, FRQ, WC-1, and WC-2, with an emphasis on the roles of protein phosphorylation. Studies on additional genes affecting clock properties are described and place these genes into two categories: those that affect the FRQ/WCC oscillator and those that do not. A discussion of temperature compensation and the mutants affecting this property is included. A section is devoted to the observations pertinent to the existence of other oscillators in this organism with respect to their properties, their effects, and their preliminary characterization. The output of the clock and the control of clock-controlled genes are discussed, emphasizing the phasing of these genes and the layers of control. In conclusion, the authors provide an outlook summarizing their suggestions for areas that would be fruitful for further exploration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.