Evidence map›Paper›PMID 21924974›Full record

ReviewAdvances in genetics2011

The itty-bitty time machine genetics of the cyanobacterial circadian clock.

Shannon R Mackey, Susan S Golden, Jayna L Ditty

Abstract readReview
In one paragraph

Review in Advances in genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
10.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  10. Article
  11. Article
  12. Relationship between Oxidative Stress, Circadian Rhythms, and AMD.Oxidative medicine and cellular longevity · 2016
    Review
  13. Toward Multiscale Models of Cyanobacterial Growth: A Modular Approach.Frontiers in bioengineering and biotechnology · 2016
    Review
  14. Article
  15. The circadian oscillator in Synechococcus elongatus controls metabolite partitioning during diurnal growth.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Shannon R MackeyBiology Department, St. Ambrose University, Davenport, Iowa, USA.
Susan S Golden
Jayna L Ditty
Saint Ambrose University · USUniversity of California, San Diego · USUniversity of St. Thomas - Minnesota · US

Funding

THE PATHWAY THAT SETS THE CYANOBACTERIAL CIRCADIAN CLOCKR01GM062419 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2001 to 2015
$3.9M
NIGMS NIH HHS GM62419NIGMS NIH HHS R01 GM062419
6 · The paper itself

Abstract

The cyanobacterium Synechococcus elongatus PCC 7942 has been used as the prokaryotic model system for the study of circadian rhythms for the past two decades. Its genetic malleability has been instrumental in the discovery of key input, oscillator, and output components and has also provided monumental insights into the mechanism by which proteins function to maintain and dictate 24-h time. In addition, basic research into the prokaryotic system has led to interesting advances in eukaryotic circadian mechanisms. Undoubtedly, continued genetic and mutational analyses of this single-celled cyanobacterium will aid in teasing out the intricacies of the Kai-based circadian clock to advance our understanding of this system as well as other more "complex" systems.

Indexed as

Biological ClocksCircadian ClocksBacterial ProteinsCircadian RhythmCyanobacteriaGene Expression Regulation, BacterialModels, BiologicalSignal TransductionBacterial Proteins

Identifiers

PMID21924974
PMCPMC3319097
OpenAlexW51192832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.