ArticlePlacenta2011
Mother's lifetime nutrition and the size, shape and efficiency of the placenta.
Article in Placenta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed.
- Maternal undernourishment impairs murine placental development during pregnancy.BMC pregnancy and childbirth · 2025Article
- Associations of placental lncRNA expression with maternal pre-pregnancy BMI and infant birthweight in two birth cohorts.Journal of developmental origins of health and disease · 2025Article
- Does Placental Efficiency and Vascularization Affect Puppy Health? A Study in Boxer and Dobermann Dogs.Animals : an open access journal from MDPI · 2024Article
- Compromised maternal nutritional status in early pregnancy and its relation to the birth size in young rural Indian mothers.BMC nutrition · 2021Article
- Preconceptional Lipid-Based Nutrient Supplementation in 2 Low-Resource Countries Results in Distinctly Different IGF-1/mTOR Placental Responses.The Journal of nutrition · 2021Article
- Ruminant Placental Adaptation in Early Maternal Undernutrition: An Overview.Frontiers in veterinary science · 2021Review
- Fetal Growth Restriction.Journal of obstetrics and gynaecology of India · 2020Review
- Epigenetically regulated imprinted gene expression associated with IVF and infertility: possible influence of prenatal stress and depression.Journal of assisted reproduction and genetics · 2019Review
- Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury.Frontiers in endocrinology · 2019Review
- Chorionic vascular "fit" in the human placenta: Relationship to fetoplacental outcomes.Placenta · 2017Article
- [Effect of serum restriction on insulin like growth factor-1 expressions and invasiveness in human trophoblast HTR-8/SVneo cells in vitro].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017Article
- Placental Origins of Chronic Disease.Physiological reviews · 2016Review
- Placental Growth Measures in Relation to Birth Weight in a Latin American Population.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016Observational
- The programming of cardiovascular disease.Journal of developmental origins of health and disease · 2015Review
- Multiscale modelling of the feto-placental vasculature.Interface focus · 2015Article
- Cohort profile: Mysore parthenon birth cohort.International journal of epidemiology · 2015Observational
- Associations between prenatal traffic-related air pollution exposure and birth weight: Modification by sex and maternal pre-pregnancy body mass index.Environmental research · 2015Article
- Maternal Factors Are Associated with the Expression of Placental Genes Involved in Amino Acid Metabolism and Transport.PloS one · 2015Article
- The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio.Placenta · 2014Article
- The Human Placenta Project: placental structure, development, and function in real time.Placenta · 2014Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundStudies have shown that the shape and size of the placenta at birth predict blood pressure in later life. The influences that determine placental morphology are largely unknown. We have examined the role of mother's body size.
methodsWe studied 522 neonates who were born in a maternity hospital in Mysore, South India. The weight of the placenta and the length and breadth of its surface, were measured after delivery.
resultsHigher maternal fat mass predicted a larger placental surface (p = 0.02), while larger maternal head circumference predicted a more oval placental surface (p = 0.03). Higher maternal fat mass and larger maternal head circumference were associated with greater placental efficiency, indicated by lower ratios of the length (p = 0.0003 and p = 0.0001 respectively) and breadth (p = 0.0002 and p < 0.0001) of the surface to birthweight. In a sub-sample of 51 mothers whose own birthweight was available, higher maternal birthweight was related to lower ratios of the length and breadth of the surface to birthweight (p = 0.01 and 0.002). Maternal height was unrelated to placental size or shape.
conclusionsHigher maternal fat mass, reflecting the mother's current nutritional state, and larger maternal head circumference, reflecting the mother's fetal/infant growth, are associated with changes in the shape and size of the placental surface and greater placental efficiency. We suggest that these associations reflect effects of the mother's nutrition at different stages of her lifecourse on the development of the placenta and on materno-placento-fetal transfer of nutrients.
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