Evidence map›Paper›PMID 2192259›Full record

ArticleMolecular and cellular biology1990

TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis.

I Laloux, E Dubois, M Dewerchin, E Jacobs

Abstract read
In one paragraph

Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
  2. Targeting TEAD in cancer.Frontiers in oncology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Tec1, a member of the TEA transcription factors family, is involved in virulence and basidiocarp development in Ustilago maydis.International microbiology : the official journal of the Spanish Society for Microbiology · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

I LalouxLabatoire de Microbiologie, Faculté des Sciences, Université Libre de Bruxelles, Belgium.
E Dubois
M Dewerchin
E Jacobs

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ty and Ty-mediated gene expression observed in haploid cells of Saccharomyces cerevisiae depends on several determinants, some of which are required for the expression of haploid-specific genes. We report here the cloning and molecular analysis of TEC1. TEC1 encodes a 486-amino-acid protein that is a trans-acting factor required for full Ty1 expression and Ty1-mediated gene activation. However, mutation or deletion of the TEC1 gene had little effect on total Ty2 transcript levels. Our analysis provides clear evidence that TEC1 is not involved in mating or sporulation processes. Unlike most of the proteins involved in Ty and adjacent gene expression, the product of TEC1 has no known cellular function. Although there was no mating-type effect on TEC1 expression, our results indicate that the TEC1 and the a/alpha diploid controls on Ty1 expression are probably not cumulative.

Indexed as

Gene Expression Regulation, FungalGenes, FungalGenes, Mating Type, FungalAllelesAmino Acid SequenceBase SequenceChromosome DeletionCloning, MolecularDNA, FungalGenotypeHaploidyMolecular Sequence DataPlasmidsRestriction MappingRNA, FungalSaccharomyces cerevisiaeDNA, FungalRNA, Fungal

Identifiers

PMID2192259
PMCPMC360789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.