ArticleThe international journal of cardiovascular imaging2012
Prognostic value of coronary artery calcium score and coronary CT angiography in patients with intermediate risk of coronary artery disease.
Article in The international journal of cardiovascular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Physical fitness in male adolescents and atherosclerosis in middle age: a population-based cohort study.British journal of sports medicine · 2024Article
- Combined evaluation of CAC score and myocardial perfusion imaging in patients at risk of cardiovascular disease: where are we and what do the data say.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Predictors of Non-Obstructive Coronary Artery Disease in Patients Undergoing Elective Coronary Angiography.Global heart · 2023Article
- Predicting coronary artery calcified plaques using perivascular fat CT radiomics features and clinical risk factors.BMC medical imaging · 2022Article
- The Diagnostic and Prognostic Value of Coronary Calcium Scoring in Stable Chest Pain Patients: A Narrative Review.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2022Review
- Diagnostic value of clinical risk scores for predicting normal stress myocardial perfusion imaging in subjects without coronary artery calcium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Imaging in Women with Heart Failure: Sex-specific Characteristics and Current Challenges.Cardiac failure review · 2022Review
- Prognostic value of CAD-RADS classification by coronary CTA in patients with suspected CAD.BMC cardiovascular disorders · 2021Article
- Computed tomography calls out nuclear imaging in its field: It doesn't matter how you are searching but what you are looking for.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Relationship between coronary artery calcification and myocardial ischemia on computed tomography myocardial perfusion in patients with stable chest pain.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- From CT to artificial intelligence for complex assessment of plaque-associated risk.The international journal of cardiovascular imaging · 2020Review
- Profile of genetic variations in severely calcified carotid plaques by whole-exome sequencing.Surgical neurology international · 2020Article
- Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis.Heart international · 2020Review
- Ischemia and No Obstructive Coronary Artery Disease ( INOCA ): What Is the Risk?Journal of the American Heart Association · 2018Review
- The effect of iterative model reconstruction on coronary artery calcium quantification.The international journal of cardiovascular imaging · 2016Article
- Plaque assessment by coronary CT.The international journal of cardiovascular imaging · 2016Review
- Beyond ultrasound: advances in multimodality cardiac imaging.Internal and emergency medicine · 2015Article
- Interscan reproducibility of quantitative coronary plaque volume and composition from CT coronary angiography using an automated method.European radiology · 2014Article
- Atherosclerosis burden in patients with acute chest pain: obesity paradox.ISRN obesity · 2014Article
- Prevalence and predictors of coronary artery disease in patients with a calcium score of zero.The international journal of cardiovascular imaging · 2013Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to compare the prognostic value of coronary calcium scoring and coronary computed tomography (CT) angiography in assessing the cardiac risk and its temporal characteristics in patients at intermediate pre-test likelihood of coronary artery disease (CAD). Cardiac CT was performed in 326 patients at intermediate (15-85%) pre-test likelihood of CAD to evaluate calcium score and presence and severity of the disease. Patients were followed-up for the occurrence of major cardiac events (cardiac death, myocardial infarction, and unstable angina requiring revascularization). During follow-up (26 ± 12 months) 34 events occurred. Calcium score, extent of CAD, and plaque extent and distribution were higher (all P < 0.001) in patients with events than in those without. No patients with calcium score of 0 had events at follow-up. Calcium score (P < 0.001), number of segments with non-calcified or mixed plaque (P < 0.05), and segments-at-risk-score (P < 0.005) were independent predictors of events. Cardiac risk was greater for all time intervals and accelerated more over time with worsening of calcium score. In presence of coronary calcium, significant CAD further increased the probability of failure for all time intervals. Therefore, patients at intermediate CAD risk without coronary calcium do not need further evaluation with longer and higher-radiation-dose protocols, while in the presence of coronary calcium CT angiography is useful to further stratify patients.
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