Trial reportPsychopharmacology2012
Characterizing smoking topography of cannabis in heavy users.
Trial report in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pharmacotherapies for cannabis use disorder.The Cochrane database of systematic reviews · 2025Pooled it
- Cannabis Use and Car Crashes: A Review.Frontiers in psychiatry · 2021Pooled it
- Pharmacotherapies for cannabis dependence.The Cochrane database of systematic reviews · 2019Pooled it
- Pharmacotherapies for cannabis dependence.The Cochrane database of systematic reviews · 2014Pooled it
- Naturalistic Topography Assessment in a Randomized Clinical Trial of Smoking Unfiltered Cigarettes: Challenges, Opportunities, and Recommendations.International journal of environmental research and public health · 2021Trial
- Oral fluid cannabinoids in chronic frequent cannabis smokers during ad libitum cannabis smoking.Drug testing and analysis · 2015Trial
- Investigating sex differences in the acute effects of smoked cannabis: a potency-ranging, controlled administration, human laboratory experiment.Psychopharmacology · 2026Article
- Quantity of delta-9-tetrahydrocannabinol consumption and cannabis use disorder among daily cannabis consumers.Addiction (Abingdon, England) · 2025Article
- The driving-related attitudes, beliefs and behaviours of cannabis users in the Australian Capital Territory following decriminalisation.Drug and alcohol review · 2025Article
- Estimating Cannabis Consumption in Milligrams of THC From Self-Reported Hit Size.Cannabis (Albuquerque, N.M.) · 2025Article
- Comparison Between Smoked Tobacco and Medical Cannabis Cigarettes Concerning Particulate Matter.Cannabis and cannabinoid research · 2024Article
- The Puzzle of Marijuana Use and Forced Vital Capacity.Annals of the American Thoracic Society · 2024Review
- An Automated "Hands-Off" Method for Sampling Mainstream Smoke from Cannabis Cigarettes.Toxics · 2024Article
- Estimating THC Consumption from Smoked and Vaped Cannabis Products in an Online Survey of Adults Who Use Cannabis.Cannabis and cannabinoid research · 2024Article
- A preliminary characterization of cannabis oil use and vaporization among individuals who use for medical purposes: A pilot study.Experimental and clinical psychopharmacology · 2024Article
- Exploring survey methods for measuring consumption quantities of cannabis flower and concentrate products.The American journal of drug and alcohol abuse · 2023Article
- Predicting Maternal and Infant Tetrahydrocannabinol Exposure in Lactating Cannabis Users: A Physiologically Based Pharmacokinetic Modeling Approach.Pharmaceutics · 2023Article
- Cannabis self-administration in the human laboratory: a scoping review of ad libitum studies.Psychopharmacology · 2023Article
- Remote detection of Cannabis-related impairments in performance?Psychopharmacology · 2022Article
- Are Sweet Dreams Made of These? Understanding the Relationship Between Sleep and Cannabis Use.Cannabis and cannabinoid research · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
rationaleLittle is known about the smoking topography characteristics of heavy cannabis users. Such measures may be able to predict cannabis use-related outcomes and could be used to validate self-reported measures of cannabis use.
objectivesThe current study was conducted to measure cannabis smoking topography characteristics during periods of ad libitum use and to correlate topography assessments with measures of self-reported cannabis use, withdrawal and craving during abstinence, and cognitive task performance.
methodsParticipants (N = 20) completed an inpatient study in which they alternated between periods of ad libitum cannabis use and abstinence. Measures of self-reported cannabis use, smoking topography, craving, withdrawal, and sleep measures were collected.
resultsParticipants smoked with greater intensity (e.g., greater volume, longer duration) on initial cigarette puffs with a steady decline on subsequent puffs. Smoking characteristics were significantly correlated with severity of withdrawal, notably sleep quality and architecture, and craving during abstinence, suggesting dose-related effects of cannabis use on these outcomes. Smoking characteristics generally were not significantly associated with cognitive performance. Smoking topography measures were significantly correlated with self-reported measures of cannabis use, indicating validity of these assessments, but topography measures were more sensitive than self-report in predicting cannabis-related outcomes.
conclusionsA dose-effect relationship between cannabis consumption and outcomes believed to be clinically important was observed. With additional research, smoking topography assessments may become a useful clinical tool.
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