ArticleCardiovascular journal of Africa
CEPHEUS SA: a South African survey on the undertreatment of hypercholesterolaemia.
Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A scoping review on natural cholesterol lowering supplements sold in South African pharmacies.Health SA = SA Gesondheid · 2024Article
- The relationship between dyslipidemia and inflammation among adults in east coast China: A cross-sectional study.Frontiers in immunology · 2022Article
- Dyslipidemias and cardiovascular risk scores in urban and rural populations in north-western Tanzania and southern Uganda.PloS one · 2019Article
- Centralized Pan-Middle East Survey on the Under-Treatment of Hypercholesterolemia: Results from the CEPHEUS II Study in Egypt.Cardiology and therapy · 2017Article
- Increasing Prescription Length Could Cut Cardiovascular Disease Burden And Produce Savings In South Africa.Health affairs (Project Hope) · 2015Article
- Centralized Pan-Middle East Survey on the Under-Treatment of Hypercholesterolemia: Results from the CEPHEUS Study in Egypt.Cardiology and therapy · 2014Article
- Prevalence of dyslipidaemia in statin-treated patients in South Africa: results of the DYSlipidaemia International Study (DYSIS).Cardiovascular journal of Africa · 2013Observational
- Gender and ethnic differences in the control of hyperlipidaemia and other vascular risk factors: insights from the CEntralised Pan-South African survey on tHE Under-treatment of hypercholeSterolaemia (CEPHEUS SA) study.Cardiovascular journal of Africa · 2013Article
- LDL Cholesterol Goal Attainment in Hypercholesterolemia: CEPHEUS Indonesian Survey.Acta Cardiologica Sinica · 2013Article
- The therapeutic management of South African dyslipidaemic patients at very high cardiovascular risk (CARDIO TRACK): a cross-sectional study.Cardiovascular journal of AfricaObservational
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11 authors.
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Abstract
aimThe aim of the CEntralised Pan-South African survey on tHE Under-treatment of hypercholeSterolaemia (CEPHEUS SA) was to evaluate the current use and efficacy of lipidlowering drugs (LLDs), and to identify possible patient and physician characteristics associated with failure, if any, to achieve low-density lipoprotein cholesterol (LDL-C) targets.
methodsThe survey was conducted in 69 study centres in South Africa and recruited consecutive consenting patients who had been prescribed LLDs for at least three months. One visit was scheduled for data collection, including fasting plasma lipid and glucose levels. Physicians and patients completed questionnaires regarding their knowledge, awareness and perceptions of hypercholesterolaemia and the treatment thereof.
resultsOf the 3 001 patients recruited, 2 996 were included in the final analyses. The mean age was 59.4 years, and 47.5% were female. Only 60.5 and 52.3% of patients on LLDs for at least three months achieved the LDL-C target recommended by the NCEP ATP III/2004 updated NCEP ATP III and the Fourth JETF/South African guidelines, respectively. Being male, older than 40 years, falling into the lower-risk categories, compliance with the medication regimen, and patient knowledge that the LDL-C goal had been reached, were associated with the highest probability of attaining LDL-C goals.
conclusionThe results of this survey highlight the sub-optimal lipid control achieved in many South African patients taking lipid-lowering therapy.
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