ArticleParkinson's disease2012
Impaired economy of gait and decreased six-minute walk distance in Parkinson's disease.
Article in Parkinson's disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of physical activity on Parkinson's disease outcomes in patients with bilateral subthalamic nucleus deep brain stimulation: a systematic review.Frontiers in neurology · 2026Pooled it
- Oxygen consumption, oxygen cost, heart rate, and perceived effort during split-belt treadmill walking in young healthy adults.European journal of applied physiology · 2013Trial
- Randomized clinical trial of 3 types of physical exercise for patients with Parkinson disease.JAMA neurology · 2013Trial
- Quantitative normative gait data in a large cohort of ambulatory persons with Parkinson's disease.PloS one · 2012Trial
- Creating and Evaluating a Prediction Equation for VO 2peak in Individuals with Early Stage, Never Medicated Parkinson's Disease.Medicine and science in sports and exercise · 2026Article
- Impact of forward and backward walking on gait parameters across parkinson's disease stages and severity: a prospective observational study.BMC neurology · 2025Observational
- Teleneurorehabilitation and Motor and Nonmotor Symptoms and Quality of Life in Parkinson Disease: The TELEPARK Randomized Clinical Trial.JAMA neurology · 2025Article
- Tango and physiotherapy interventions in Parkinson's disease: a pilot study on efficacy outcomes on motor and cognitive skills.Scientific reports · 2024Article
- How groove in music affects gait.Experimental brain research · 2021Article
- Fatigability and Cardiorespiratory Impairments in Parkinson's Disease: Potential Non-Motor Barriers to Activity Performance.Journal of functional morphology and kinesiology · 2020Review
- Accuracy and Precision of Three Consumer-Grade Motion Sensors During Overground and Treadmill Walking in People With Parkinson Disease: Cross-Sectional Comparative Study.JMIR rehabilitation and assistive technologies · 2020Article
- Rethinking energy in parkinsonian motor symptoms: a potential role for neural metabolic deficits.Frontiers in systems neuroscience · 2014Article
- The impact of a submaximal level of exercise on balance performance in older persons.TheScientificWorldJournal · 2014Article
- The Unified Parkinson's Disease Rating Scale as a predictor of peak aerobic capacity and ambulatory function.Journal of rehabilitation research and development · 2012Article
- Feasibility of a mobile feedback system for gait retraining in people with lower limb loss-A technical note.Journal of rehabilitation and assistive technologies engineeringArticle
- Oxygen uptake efficiency slope: A submaximal test evaluation tool that provides cardiopulmonary reserve data in individuals with Parkinson's disease.Brazilian journal of physical therapyObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Changes in the biomechanics of gait may alter the energy requirements of walking in Parkinson's Disease (PD). This study investigated economy of gait during submaximal treadmill walking in 79 subjects with mild to moderate PD and the relationship between gait economy and 6-minute walk distance (6 MW). Oxygen consumption (VO(2)) at the self-selected treadmill walking speed averaged 64% of peak oxygen consumption (VO(2) peak). Submaximal VO(2) levels exceeded 70% of VO(2) peak in 30% of the subjects. Overall the mean submaximal VO(2) was 51% higher than VO(2) levels expected for the speed and grade consistent with severe impairment in economy of gait. There was an inverse relationship between economy of gait and 6MW (r = -0.31, P < 0.01) and with the self-selected walking speed (r = -0.35, P < 0.01). Thus, the impairment in economy of gait and decreased physiologic reserve result in routine walking being performed at a high percentage of VO(2) peak.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.