ArticleOxidative medicine and cellular longevity2011
Cytokines and oxidative stress status following a handball game in elite male players.
Article in Oxidative medicine and cellular longevity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Pooled it
- Physical Demands during Official Competitions in Elite Handball: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- The Effect of Post-Exercise Cryotherapy on Recovery Characteristics: A Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Effects of exergaming on cardiovascular risk factors and adipokine levels in women.The journal of physiological sciences : JPS · 2018Trial
- Fermented milk improves glucose metabolism in exercise-induced muscle damage in young healthy men.Nutrition journal · 2013Trial
- Acute Biochemical Responses to Competitive Tournament Load in Female Handball Players: Hormonal, Inflammatory and Muscle Damage Markers.Life (Basel, Switzerland) · 2026Article
- The Effects of Antioxidant Supplementation on Soccer Performance and Recovery: A Critical Review of the Available Evidence.Nutrients · 2024Review
- Oxidative status alteration during aerobic-dominant mixed and anaerobic-dominant mixed effort in judokas.Heliyon · 2023Article
- A Systematic Review and Meta-Analysis of Tai Chi Training in Cardiorespiratory Fitness of Elderly People.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Effect of Resistance Training With Total and Partial Blood Flow Restriction on Biomarkers of Oxidative Stress and Apoptosis in Untrained Men.Frontiers in physiology · 2021Article
- Intermittent Hypoxic Exposure Reduces Endothelial Dysfunction.BioMed research international · 2020Article
- Can Milk Affect Recovery from Simulated Team-Sport Match Play?Nutrients · 2019Article
- Impairment between Oxidant and Antioxidant Systems: Short- and Long-term Implications for Athletes' Health.Nutrients · 2019Review
- Postmatch recovery of physical performance and biochemical markers in team ball sports: a systematic review.BMJ open sport & exercise medicine · 2018Article
- The influence of hypoxic physical activity on cfDNA as a new marker of vascular inflammation.Archives of medical science : AMS · 2015Article
- On-court demands of elite handball, with special reference to playing positions.Sports medicine (Auckland, N.Z.) · 2014Review
- Oxidative stress and total antioxidant capacity in handball players.Advanced biomedical research · 2014Article
- Exercise training-induced changes in inflammatory mediators and heat shock proteins in young tennis players.Journal of sports science & medicine · 2013Article
- Comment on "Cytokines and oxidative stress status following a handball game in elite male players".Oxidative medicine and cellular longevity · 2012Article
- Does High Volume of Exercise Training Increase Aseptic Vascular Inflammation in Male Athletes?American journal of men's healthArticle
Corrections and comments
- Commented on by
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHandball is considered an intermittent sport that places an important stress on a player's aerobic and anaerobic metabolism. However, the oxidative stress responses following a handball game remain unknown. We investigated the responses of plasma and erythrocyte antioxidant system and oxidative stress biomarkers following a single handball game.
methodsFourteen male elite Brazilian handball athletes were recruited in the present study. Blood samples were taken before, immediately, and 24 hours after the game.
resultsAfter the game and during 24 hours of recovery, the concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (thiol groups and reduced glutathione decreased, whereas TBARS and plasma antioxidant capacity was increased) as well as in erythrocyte (increased levels of TBARS and protein carbonyls). Erythrocyte antioxidant enzyme activities were also significantly changed by handball. Muscle damage indices (creatine kinase and lactate dehydrogenase) increased significantly after exercise. In addition, IL-6 increased after the game, whereas TNF-α decreased during recovery.
conclusionThis study demonstrates that a single handball game in elite athletes induces a marked state of oxidative stress evidenced by the oxidative modification in plasma and erythrocyte macromolecules, as well as by changes in the enzymatic and nonenzymatic antioxidant system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.