Evidence map›Paper›PMID 21921576›Full record

ArticlePublic health genomics2012

Skin cancer concerns and genetic risk information-seeking in primary care.

J Hay, K A Kaphingst, R Baser, Y Li, S Hensley-Alford, C M McBride

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Public health genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03130569 (Personalized Genomic Testing for Skin Cancer - Maximizing Utility and Reach), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03130569 nacompletednot on this mapstarted 2015, after this paper: background citation

Personalized Genomic Testing for Skin Cancer - Maximizing Utility and Reach

TypeinterventionalSponsorUniversity of New MexicoRan2015 to 2017Enrolled600ConditionsMelanoma (Skin)ArmsWeb-based Module Group
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
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  6. Interest and Utility ofJournal of skin cancer · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

J HayDepartments of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10022, USA. hayj@mskcc.org
K A Kaphingst
R Baser
Y Li
S Hensley-Alford
C M McBride
Memorial Sloan Kettering Cancer Center · USHenry Ford Hospital · USInstitute of Behavioral Sciences · JPNational Human Genome Research Institute · USWashington University in St. Louis · US

Funding

The HMO Cancer Research Network (CRN)U19CA079689 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI MAZOR, KATHLEEN MICHELE · 1999 to 2011
$62.6M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
Multiplex InitiativeZIAHG200344 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI MC BRIDE, COLLEEN M · 2009 to 2013
$3.9M
Perception of Gene-Environment Cancer Risks in MelanomaK07CA098106 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HAY, JENNIFER L · 2003 to 2007
$672k
Measuring real time decision-making about UVR ProtectionR21CA137532 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HAY, JENNIFER L · 2009 to 2010
$459k
Cancer Risks Beliefs & ScreeningR21CA133376 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HAY, JENNIFER L · 2009 to 2010
$457k
NCI NIH HHS CA133376NCI NIH HHS CA137532NCI NIH HHS CA98106NCI NIH HHS K07 CA098106NCI NIH HHS R21 CA133376NCI NIH HHS R21 CA137532NCI NIH HHS U19 CA 079689NCI NIH HHS U19 CA079689NCRR NIH HHS UL1 RR024996NCRR NIH HHS UL1-RR024996NHGRI NIH HHS HHSN268200782096C
6 · The paper itself

Abstract

backgroundGenomic testing for common genetic variants associated with skin cancer risk could enable personalized risk feedback to motivate skin cancer screening and sun protection.

methodsIn a cross-sectional study, we investigated whether skin cancer cognitions and behavioral factors, sociodemographics, family factors, and health information-seeking were related to perceived importance of learning about how (a) genes and (b) health habits affect personal health risks using classification and regression trees (CART).

resultsThe sample (n = 1,772) was collected in a large health maintenance organization as part of the Multiplex Initiative, ranged in age from 25-40, was 53% female, 41% Caucasian, and 59% African-American. Most reported that they placed somewhat to very high importance on learning about how genes (79%) and health habits (88%) affect their health risks. Social influence actors were associated with information-seeking about genes and health habits. Awareness of family history was associated with importance of health habit, but not genetic, information-seeking.

conclusionsThe investment of family and friends in health promotion may be a primary motivator for prioritizing information-seeking about how genes and health habits affect personal health risks and may contribute to the personal value, or personal utility, of risk information. Individuals who seek such risk information may be receptive to interventions aimed to maximize the social implications of healthy lifestyle change to reduce their health risks.

Indexed as

Genetic Predisposition to DiseaseHealth BehaviorHealth Knowledge, Attitudes, PracticeHealth PromotionPrimary Health CareAdultCross-Sectional StudiesFemaleGenetic TestingHumansMaleSkin Neoplasms

Identifiers

PMID21921576
PMCPMC3318939
OpenAlexW2086181883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.