Evidence map›Paper›PMID 21920869›Full record

ArticleAJNR. American journal of neuroradiology2011

Multiparametric MR imaging of sinonasal diseases: time-signal intensity curve- and apparent diffusion coefficient-based differentiation between benign and malignant lesions.

M Sasaki, M Sumi, S Eida, Y Ichikawa, T Sumi, T Yamada, T Nakamura

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Article in AJNR. American journal of neuroradiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

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12citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

M SasakiDepartment of Radiology and Cancer Biology, Nagasaki University School of Dentistry, Nagasaki, Japan.
M Sumi
S Eida
Y Ichikawa
T Sumi
T Yamada
T Nakamura

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe sinonasal region is a platform for a broad spectrum of benign and malignant diseases, and image-based differentiation between benign and malignant diseases in this area is often difficult. Here, we evaluated multiparametric MR imaging with combined use of TICs and ADCs for the differentiation between benign and malignant sinonasal tumors and tumorlike diseases. MATERIALS AND

methodsTICs obtained from dynamic contrast-enhanced MR imaging and ADCs were analyzed on a lesion-by-lesion (overall TIC and ADC) and pixel-by-pixel (TIC and ADC mapping) basis in patients with benign (n = 21) or malignant (n = 23) sinonasal tumors and tumorlike diseases. The TICs were semiautomatically classified into 5 distinctive patterns (flat, slow uptake, rapid uptake with low washout ratio, rapid uptake with high washout ratio, and miscellaneous). ADCs were determined by using b-values of 500 and 1000 s/mm(2).

resultsMalignant sinonasal tumors had small (<25%) areas of the type 1 flat TIC profile as determined by pixel-by-pixel TIC analysis and large (≥50%) areas of low or extremely low ADCs (≤1.2 × 10(-3) mm(2/)s) as determined by ADC mapping. Consequently, stepwise classification on the basis of TICs and ADCs successfully (at 100% accuracy) discriminated malignant from benign sinonasal diseases in the present patient cohort.

conclusionsMultiparametric MR imaging by using TICs and ADCs may help differentiate benign and malignant sinonasal diseases.

Indexed as

AlgorithmsDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMiddle AgedParanasal Sinus NeoplasmsReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21920869
PMCPMC7964410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.