SynthesisBMJ clinical evidence2011
Neonatal jaundice.
Synthesis in BMJ clinical evidence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 18 citations in OpenAlex.
- A novel medical device that combines filtered sunlight phototherapy and kangaroo care to treat neonatal jaundice: bench feasibility study.Pediatric research · 2026Article
- Skin residual bilirubin volume: a physiologically informed framework for transcutaneous bilirubin interpretation in neonates.Frontiers in pediatrics · 2026Article
- The timing of using IVIG for neonatal ABO hemolytic disease.BMC pediatrics · 2025Article
- [Risk factors and construction of a risk prediction model for readmission due to hyperbilirubinemia in neonates with ABO hemolytic disease of the newborn].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.Nature communications · 2024Article
- Risk of low levels of blood group antibodies mediating hemolysis in ABO-incompatible neonates with negative three hemolysis tests.Frontiers in pediatrics · 2024Article
- Intravenous immunoglobulin G therapy for neonatal hyperbilirubinemia.Pediatric research · 2023Article
- Article
- Demystifying non-invasive approaches for screening jaundice in low resource settings: a review.Frontiers in pediatrics · 2023Review
- Efficacy of kangaroo mother care combined with neonatal phototherapy in newborns with non-pathological jaundice: A meta-analysis.Frontiers in pediatrics · 2023Review
- Case report: A case of spinal muscular atrophy in a preterm infant: risks and benefits of treatment.Frontiers in neurology · 2023Article
- Rolling stones: an instructive case of neonatal cholestasis.BMC pediatrics · 2022Article
- Acute and early developmental outcomes of children with Duarte galactosemia.JIMD reports · 2022Article
- A review of existing neonatal hyperbilirubinemia guidelines in Indonesia.F1000Research · 2022Review
- Efficacy of transcutaneous bilirubinometry as compared to serum bilirubin in preterm newborn during phototherapy.European journal of pediatrics · 2021Observational
- Article
- Challenges in developing a consensus definition of neonatal sepsis.Pediatric research · 2020Review
- Transcutaneous bilirubinometry during and after phototherapy in preterm infants: a prospective observational study.BMJ paediatrics open · 2020Article
- Prevalence and burden of illness of treated hemolytic neonatal hyperbilirubinemia in a privately insured population in the United States.BMC pediatrics · 2019Article
- A Survey of Practice and Knowledge of Refugee and Migrant Pregnant Mothers Surrounding Neonatal Jaundice on the Thailand-Myanmar Border.Journal of tropical pediatrics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAbout 50% of term and 80% of preterm babies develop jaundice, which usually appears 2 to 4 days after birth, and resolves spontaneously after 1 to 2 weeks. Jaundice is caused by bilirubin deposition in the skin. Most jaundice in newborn infants is a result of increased red cell breakdown and decreased bilirubin excretion. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for unconjugated hyperbilirubinaemia in term and preterm infants? We searched Medline, Embase, The Cochrane Library, and other important databases up to February 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 42 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review we present information relating to the effectiveness and safety of the following interventions: albumin infusion, exchange transfusion, home phototherapy, immunoglobulin, hospital phototherapy, and tin-mesoporphyrin.
Indexed as
Identifiers
21920055PMC3217664W4300464970What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.