Evidence map›Paper›PMID 21920050›Full record

ArticleGenome biology2011

The promise and limitations of population exomics for human evolution studies.

Jacob A Tennessen, Timothy D O'Connor, Michael J Bamshad, Joshua M Akey

Abstract read
In one paragraph

Article in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Efficient genome-wide genotyping strategies and data integration in crop plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. The exome factor.Genome biology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacob A TennessenDepartment of Genome Sciences, University of Washington, 3720 15th Ave NE, Box 355065, Seattle, WA 98195-5065, USA.
Timothy D O'Connor
Michael J Bamshad
Joshua M Akey

Funding

Genome-Wide Analysis of Adaptive Evolution in HumansR01GM076036 · NIGMS · UNIVERSITY OF WASHINGTON · PI AKEY, JOSHUA MICHAEL · 2006 to 2010
$1.3M
NHLBI NIH HHS HL-102923NIGMS NIH HHS 1R01GM076036
6 · The paper itself

Abstract

Exome sequencing is poised to yield substantial insights into human genetic variation and evolutionary history, but there are significant challenges to overcome before this becomes a reality.

Indexed as

Evolution, MolecularExomeDemographyGenetics, PopulationGenetic VariationGenome, HumanGenomicsHumansSelection, GeneticSequence Analysis, DNA

Identifiers

PMID21920050
PMCPMC3308040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.