Evidence map›Paper›PMID 21918019›Full record

ArticleJournal of clinical microbiology2011

Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States.

Jennifer M Adams-Haduch, Ezenwa O Onuoha, Tatiana Bogdanovich, Guo-Bao Tian, Jonas Marschall, Carl M Urban, Brad J Spellberg, Diane Rhee, Diane C Halstead, Anthony W Pasculle and 1 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Article
  3. Characterization and genomic analysis of the highly virulentAntimicrobial agents and chemotherapy · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
  9. Article
  10. Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  11. Genomic Analysis ofAntibiotics (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Molecular Epidemiology of Carbapenem-ResistantMicrobial drug resistance (Larchmont, N.Y.) · 2022
    Article
  14. Article
  15. Article
  16. Prevalence of carbapenemase-producing organisms among hospitalized solid organ transplant recipients, five US hospitals, 2019-2020.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer M Adams-HaduchDivision of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA.
Ezenwa O Onuoha
Tatiana Bogdanovich
Guo-Bao Tian
Jonas Marschall
Carl M Urban
Brad J Spellberg
Diane Rhee
Diane C Halstead
Anthony W Pasculle
Yohei Doi

Funding

Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Multidrug-Resistant Acinetobacter baumanniiK22AI080584 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI · 2009 to 2010
$269k
NCATS NIH HHS KL2 TR000450NIAID NIH HHS K22 AI080584NIAID NIH HHS K22AI80584
6 · The paper itself

Abstract

Acinetobacter baumannii is emerging as an important nosocomial pathogen worldwide. We report molecular epidemiology of 65 carbapenem-nonsusceptible A. baumannii isolates identified from hospitals in New York, Pennsylvania, Florida, Missouri, Nevada, and California between 2008 and 2009. All isolates were subjected to pulsed-field gel electrophoresis (PFGE). Select isolates then underwent multilocus sequence typing (MLST). While the PFGE patterns tended to cluster within each hospital, sequence types (STs) belonging to the clonal complex 92 (CC92) and the pan-European clonal lineage II (EUII; worldwide clonal lineage 2) were predominant in all hospitals. Of them, ST122 and ST208 were the most common and were found in four of the six hospitals. Isolates belonging to the pan-European clonal lineages I and III were identified in one hospital each. Carbapenemase-encoding genes bla(OXA-23) and/or ISAba1-bla(OXA-51-like) were present among the majority of isolates. These findings suggest that carbapenem-nonsusceptible A. baumannii isolates found in U.S. hospitals constitute part of the global epidemic driven by CC92, but have unique STs other than ST92, which may be spreading by means of patient transfer between health care facilities within the United States.

Indexed as

beta-Lactam ResistanceAcinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsCarbapenemsCluster AnalysisCross InfectionElectrophoresis, Gel, Pulsed-FieldHumansMolecular EpidemiologyMolecular TypingUnited StatesAnti-Bacterial AgentsCarbapenems

Identifiers

PMID21918019
PMCPMC3209126

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.