Evidence map›Paper›PMID 21917746›Full record

ArticleAdvances in dental research2011

Scientific frontiers: emerging technologies for salivary diagnostics.

B J Baum, J R Yates, S Srivastava, D T W Wong, J E Melvin

Abstract read
In one paragraph

Article in Advances in dental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Saliva proteomics updates in biomedicine.Journal of biological research (Thessalonike, Greece) · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics.International journal of molecular sciences · 2015
    Review
  13. Review
  14. Review
  15. Article
  16. Great expectorations: the potential of salivary 'omic' approaches in neonatal intensive care.Journal of perinatology : official journal of the California Perinatal Association · 2014
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B J BaumMolecular Physiology and Therapeutics Branch, NIDCR, NIH, Bethesda, MD 20892, USA.
J R Yates
S Srivastava
D T W Wong
J E Melvin

Funding

NIDCR DIR Secretory Mechanisms and Dysfunctions SectionZIADE000738 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI MELVIN, JAMES · 2011 to 2019
$14.4M
Catalogue of Human Salivary Secretory ComponentsU01DE016267 · NIDCR · SCRIPPS RESEARCH INSTITUTE, THE · PI YATES, JOHN ROBERT · 2004 to 2007
$5.2M
Genomics and Proteomics of Oral Precancer ProgressionR01DE015970 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2004 to 2009
$1.9M
Collection, Stabilization and Storage of Saliva Samples for Cancer ResearchR21CA126733 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2008 to 2009
$381k
Intramural NIH HHSNCI NIH HHS R21 CA0126733NCI NIH HHS R21 CA126733NIDCR NIH HHS R01 DE015970NIDCR NIH HHS R01 DE15970NIDCR NIH HHS U01 DE016267
6 · The paper itself

Abstract

Saliva, a biofluid historically well-studied biochemically and physiologically, has entered the post-genomic 'omics' era, where its proteomic, genomic, and microbiome constituents have been comprehensively deciphered. The translational path of these salivary constituents has begun toward a variety of personalized individual medical applications, including early detection of cancer. Salivary diagnostics is a late-comer, but it is catching up where dedicated resources, like the Salivaomics Knowledge Base (SKB), now have taken center stage in the dissemination of the diagnostic potentials of salivary biomarkers and other translational and clinical utilities.

Indexed as

Biomarkers, TumorKnowledge BasesSalivaSalivary Proteins and PeptidesDiagnosis, OralEarly Detection of CancerHumansMetagenomeProteomicsBiomarkers, TumorSalivary Proteins and Peptides

Identifiers

PMID21917746
PMCPMC3172997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.