ArticleThe Plant cell2011
Condensin II alleviates DNA damage and is essential for tolerance of boron overload stress in Arabidopsis.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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Who cites it
69 citing papers in PubMed, 152 citations in OpenAlex.
- Boron toxicity, tolerance, and accumulation potential in halophyte and salt-tolerant species.Planta · 2026Review
- Unveiling core genomic regions shaping plant architecture, productivity, and seed quality traits in sesame (Sesamum indicum L.): insights from Meta-QTL study into breeding targets.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Condensin and topoisomerases cooperate to relieve topological stress at stalled replication forks.Nature communications · 2026Article
- Convergent evolution increases boron transport through SNPs and tandem duplications atProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Deciphering the Boron Toxicity Tolerance Mechanisms ofLife (Basel, Switzerland) · 2026Article
- BMI1s interact with condensin complexes to regulate chromatin 3D structure and gene expression inaBIOTECH · 2025Article
- SUPPRESOR OF GAMMA RESPONSE 1 promotes early onset of endoreplication upon DNA double-strand breaks by inducing CCS52A1 expression in Arabidopsis roots.Journal of plant research · 2025Article
- Impact of High-Temperature Stress on Maize Seed Setting: Cellular and Molecular Insights of Thermotolerance.International journal of molecular sciences · 2025Review
- Transport and regulatory mechanisms of boron in plants.Frontiers in plant science · 2025Review
- Crosstalk among plant hormone regulates the root development.Plant signaling & behavior · 2024Review
- Phenylmercury stress induces root tip swelling through auxin homeostasis disruption.Plant molecular biology · 2024Article
- The Bor1 elevator transport cycle is subject to autoinhibition and activation.Nature communications · 2024Article
- Mechanistic insights into DNA damage recognition and checkpoint control in plants.Nature plants · 2024Review
- Article
- Chronic Ionizing Radiation of Plants: An Evolutionary Factor from Direct Damage to Non-Target Effects.Plants (Basel, Switzerland) · 2023Review
- Article
- Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays.eLife · 2022Article
- Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins.Nature plants · 2022Article
- Proteomic Response ofInsects · 2022Article
- TEB/POLQ plays dual roles in protecting Arabidopsis from NO-induced DNA damage.Nucleic acids research · 2022Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although excess boron (B) is known to negatively affect plant growth, its molecular mechanism of toxicity is unknown. We previously isolated two Arabidopsis thaliana mutants, hypersensitive to excess B (heb1-1 and heb2-1). In this study, we found that HEB1 and HEB2 encode the CAP-G2 and CAP-H2 subunits, respectively, of the condensin II protein complex, which functions in the maintenance of chromosome structure. Growth of Arabidopsis seedlings in medium containing excess B induced expression of condensin II subunit genes. Simultaneous treatment with zeocin, which induces DNA double-strand breaks (DSBs), and aphidicolin, which blocks DNA replication, mimicked the effect of excess B on root growth in the heb mutants. Both excess B and the heb mutations upregulated DSBs and DSB-inducible gene transcription, suggesting that DSBs are a cause of B toxicity and that condensin II reduces the incidence of DSBs. The Arabidopsis T-DNA insertion mutant atr-2, which is sensitive to replication-blocking reagents, was also sensitive to excess B. Taken together, these data suggest that the B toxicity mechanism in plants involves DSBs and possibly replication blocks and that plant condensin II plays a role in DNA damage repair or in protecting the genome from certain genotoxic stressors, particularly excess B.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.